Proctology

Proctology (pronounced prok-tol-uh-jee)

(1) Historically, the branch of medicine dealing with the surgery of the colon, rectum, and anus.

(2) In modern use, colorectal surgery as a specialty inside (as it were) proctology.

(3) A department or building so named in a hospital, university or clinic etc.

1896: The construct was procto- +‎ -logy or proct- + -ology.  Procto was from a Latinized form of the Greek prōktos (anus), from the primitive Indo-European prokto-, the source also of Armenian erastan-k' (buttocks).  The suffix -ology was formed from -o- (as an interconsonantal vowel) +‎ -logy.  The origin in English of the -logy suffix lies with loanwords from the Ancient Greek, usually via Latin and French, where the suffix (-λογία) is an integral part of the word loaned (eg astrology from astrologia) since the sixteenth century.  French picked up -logie from the Latin -logia, from the Ancient Greek -λογία (-logía).  Within Greek, the suffix is an -ία (-ía) abstract from λόγος (lógos) (account, explanation, narrative), and that a verbal noun from λέγω (légō) (I say, speak, converse, tell a story).  In English the suffix became extraordinarily productive, used notably to form names of sciences or disciplines of study, analogous to the names traditionally borrowed from the Latin (eg astrology from astrologia; geology from geologia) and by the late eighteenth century, the practice (despite the disapproval of the pedants) extended to terms with no connection to Greek or Latin such as those building on French or German bases (eg insectology (1766) after the French insectologie; terminology (1801) after the German Terminologie).  Within a few decades of the intrusion of modern languages, combinations emerged using English terms (eg undergroundology (1820); hatology (1837)).  In this evolution, the development may be though similar to the latter-day proliferation of “-isms” (fascism; feminism etc).  A physician specializing in proctology is a proctologist although some may prefer the punchier construction Bart Simpson (from the cartoon TV series The Simpsons), used: “butt doctor”.  The noun proctalgia (pain in the anus or rectum) existed in the medical literature as early as 1811 while the first known use of “proctologist” dates from 1897.  Proctology & proctologist are nouns and proctologic & proctological are adjectives; the noun plural is protologists.

In 1974, The British Medical Journal (BMJ) used the term “guitar nipple” to describe “the irritation to the breast that can occur from the pressure of the guitar against the body.”  In the same spirit, two years later a contributor to the Journal of the American Medical Association (JAMA) was more imaginative still, coining “hot pants syndrome” when documenting cases in which a burn to the skin had been induced by a patient carrying a battery-powered transistor radio in the pocket of their trousers.  There was also in 1978 the New England Journal of Medicine's (NEJM) “disco digit” which referred to “a sore or infected finger caused by too much finger snapping while dancing.”  These terms were indicative of the trend in the English-speaking world for newly-identified (and in some cases novel conditions) to be constructed with English elements, rather than the Latin historically used.  In the fields of proctology, the historic terms (of discomfort in the region) were:

Rectalgia (pain in the rectum), the construct being rect- (a clipping of the New Latin rectum, itself a clipping of the Latin rectum intestinum (literally “the straight intestine”), neuter of rectus (straight) +‎ -algia (from the New Latin -algia (pain), from the Ancient Greek ἄλγος (álgos) (pain).

Proctalgia (pain in the anal or rectal region), the construct being proct- (a New Latin combining form, from Ancient Greek πρωκτός (prōktós) (anus).+‎ -algia.

Anodynia (anal pain; anorectal pain), the construct being ano- (from the Latin anus) + -dynia (an alternative (used when the preceding morpheme has a terminal vowel) form of -odynia (a New Latin combining form, from the Ancient Greek ὀδύνη (odúnē) (sorrow, grief, anguish, unhappiness).

Confusingly though, because terminology evolved often independently an in parallel, medicine contrived to use anodynia also to mean “the absence of pain in a previously painful region” and in that case the construct differed, being an- (from the Ancient Greek ἀν- (an-); a doublet of un- and in- (used her in the sense of a negation) +‎ odynia (a New Latin combining form, from the Ancient Greek ὀδύνη (odúnē) (sorrow, grief, anguish, unhappiness).  So for the non-medically trained, confusion could arise given anodynia can mean either “pain in the butt” or “pain has gone away” although because it’s a word unlikely much to be seen by other than the medically trained, instances of this have presumably been rare.  But in the context of “butt pain” there would seem to be some overlap in meaning between rectalgia, proctalgia & anodynia but while all are used to refer to “pain in or around the rectal area”, in the profession there are distinctions in use, particularly in clinical and diagnostic work 

Rectalgia is used to describe pain localized in the rectum and tends to be used as general term for the condition and often without specifying a cause.  Conditions associated with rectalgia include anorectal abscesses and fissures.  Proctalgia encompasses pain in the anorectal region (both anus and rectum) and is commonly used of proctalgia fugax, a specific condition characterized by sudden, severe, and brief rectal pain with no obvious underlying cause.  As the etymology suggests, proctalgia’s remit is broader than that of rectalgia because it includes both anus and rectum.  Whether or not related to the duality of meaning, anodynia is now not in general clinical use but historically it referred to pain in the vicinity of the anus.  The modern terms for that are “anal pain” & “anorectal pain”.  So, although lay-readers might be forgiven for thinking they could be used interchangeably, clinicians applied them based on anatomical location: rectalgia (rectum), anodynia (anus) &, proctalgia (anorectal region).

In the thoughts of Kellyanne Conway: A protologist's ultrasonic rectal probe (available in 140 & 200 mm (5½ & 8 inch) length versions) by the Electro Surgical Instrument Company (ESI (1896)).

Protology and pains in the butt do feature in idiomatic use in English.  Kellyanne Conway (b 1967; senior counselor to the US president, 2017-2020) when discussing the “Muller probe” (an investigation by special counsel Robert Mueller (1944) into Donald Trump (b 1946; US president 2017-2021; president elect 2024) and the matter of alleged Russian interference in the 2016 US presidential election) told a press conference the whole project was “a political proctology exam.”  She clearly liked the imagery because later, when Mr Muller handed down his report, she told the assembled press pack it was the “best day” since Mr Trump’s (2016) election, repeated the phrase “political proctology” and, sticking with medical allusions, said the verdict delivered “a clean bill of health.”

PITB (and its variations) is widely used.

Kellyanne Conway in hoodie: Miss January, Clare Boothe Luce Policy Institute's annual Conservative Women Calendar (2009).

So like Mr Trump, Ms Conway would have found the Muller probe a (metaphorical) pain in the butt but “political proctology exam” was both a more polite and elegant way of saying it.  The saying “pain in the butt” belongs to a class of such expressions (all meaning “a nuisance; a source of trouble or annoyance”) which variously are used according to the need for politeness, the hierarchy of rudeness (in ascending order) being: “pain in the neck”, “pain in the brain”, “pain in the back” (all about equal), “pain in the rear”, “pain in the bum”, “pain in the ass” & “pain in the arse” (the choice between “ass” & “arse” dictated by linguistic tradition).  All are often used as initializms (PITN PITB, PITR, PITA) and PITA seems the most popular while in oral use “pain in the neck” and “pain in the ass (arse)” vie for popularity although some do like “pain in the brain” for the rhyme.

First edition (hardcover, 1956) of Soranus' Gynecology, published by Johns Hopkins University Press, translated and with an introduction by Owsei Temkin MD (1902-2002).

Quite when the idea of “specialists” in the modern sense of the word came to the practice of medicine isn’t certain but long before such things were formalized by the creation of colleges or specialist qualifications, it’s likely the early physicians did tend to develop particular areas of expertise and would have had certain patients referred to them, much as is the modern practice.  Probably, this emergence of specialties would have happened organically, based on geography: a physician in a fishing community on the sunny Aegean coast would have encountered a different patient profile than one who worked in the cold of the mountains.  Thus, while it’s not known who can be though the “first proctologist”, medical students everywhere will probably nominate Soranus of Ephesus, a Greek physician who practiced in both Alexandria and Rome during the first & second century AD.  His four-volume treatise on gynecology still exists so he probably deserves to be remembered as an early gynecologist but, as many medical students will confirm, his name is pronounced sawr-ey-nuhs so a proto-proctologist he must be.  Such things do happen: Winston Churchill’s (1875-1965; UK prime-minister 1940-1945 & 1951-1955) neurologist was Russell Brain (1895–1966).

Inquire & Enquire

Inquire (pronounced in-kwahyuhr)

(1) To seek information by questioning; to ask.

(2) To make an investigation (usually followed by into).

(3) To seek (obsolete).

(4) To question (a person) (obsolete).

1250–1300: From the Middle English enqueren & anqueren (to ask (a question), ask about, ask for (specific information); learn or find out by asking, seek information or knowledge; to conduct a legal or official investigation (into an alleged offense)), from the Latin inquīrere (to seek for), replacing the Middle English enqueren, from the Old French enquerre, also from Latin.  The construct in Latin was from in- (into) + quaerere (to seek).  The prefix -in is quirky because it can act either to negate or intensify.  The general rule is that when prepended to a noun or adjective, it reinforces the quality signified and when prepended to an adjective, it negates the meaning, the latter mostly in words borrowed from French.  The Latin prefix in- was from the Proto-Italic en-, from the primitive Indo-European n̥- (not), the zero-grade form of the negative particle ne (not) and was akin to ne-, nē & nī.  In Modern English it is from the Middle English in-, from Old English in- (in, into), from the Proto-Germanic in, from the primitive Indo-European en.  Inquiry & inquirer are nouns, inquiring is a noun, verb & adjective, inquires is a verb, inquirable & inquisitive are adjective and inquiringly is an adverb; the noun plural is inquiries.  The verb inquireth is listed by most as archaic and forms such as reinquired & reinquiring have been coined as needed.

So the in- in inquire is not related to in- (not), also a common prefix in Latin and this created a tradition of confusion which persists to this day.  In Ancient Rome, impressus could mean "pressed" or "unpressed; inaudire meant "to hear" but inauditus meant "unheard of; invocatus was "uncalled, uninvited," but invocare was "to call, appeal to".  In Late Latin investigabilis could mean "that may be searched into" or "that cannot be searched into”.  English picked up the confusion and it’s not merely a linguistic quirk because mixing up the meaning of inflammable could have ghastly consequences.  Fortunately, some of the duplicity has died out: Implume, noted from the 1610s meant "to feather," but implumed (from a decade or more earlier meant "unfeathered".  Impliable could be held to mean "capable of being implied" (1865) or "inflexible" (1734).  Impartible in the seventeenth century simultaneously could mean "incapable of being divided" or "capable of being imparted" and, surprisingly, impassionate can mean "free from passion" or "strongly stirred by passion" (used wrongly that certainly could have inintended consequences).  The adjective inanimate was generally understood to indicate "lifeless" but John Donne (1572–1631), when using inanimate as a verb meant "infuse with life or vigor." Irruption is "a breaking in" but irruptible is "unbreakable".

In addition to improve "use to one's profit", Middle English also had the fifteenth century verb improve meaning "to disprove".  To inculpate is "to accuse," but inculpable means "not culpable, free from blame".  Infestive (a creation of the 1560s, from infest) originally meant "troublesome, annoying" but by the 1620s meant "not festive".  Bafflingly, in Middle English, inflexible could mean both "incapable of being bent" or "capable of being swayed or moved".  During the seventeenth century, informed could mean "current in information" formed, animated" or "unformed, formless", an unhelpful situation the Oxford English Dictionary (OED) described as “an awkward use".  Just a bizarre was that in the mid-sixteenth century inhabited meant "dwelt in" yet within half-a-century was being used to describe "uninhabited".  Some dictionaries insist the adjectives unenquired & unenquiring really exist but there’s scant evidence of use.  A noted derivation with some history is inquisitor.  Synonyms and words with a similar sense include examine, inspect, interrogate, investigate, analyze, catechize, explore, grill, hit, knock, probe, check, prospect, pry, query, question, roast, scrutinize, search, seek & sift.

Enquire (pronounced en-kwahyuhr)

A variant form of inquire

Circa 1300: From the Middle English enqueren & anqueren, (to ask (a question), to ask about, to ask for (specific information); learn or find out by asking, seek information or knowledge; to conduct a legal or official investigation (into an alleged offense)), from the Old French enquerre (to ask, inquire about) (which persists in Modern French as enquérir) and directly from the Medieval Latin inquīrere (to seek for).  As long ago as the fourteenth century the spelling of the English word was changed following the Latin model, but, in the annoying way that happens sometimes in English, the half-Latinized enquire persists and some people have even invented “rules” about when it should be used instead of inquire.   Sensibly, the Americans ignore these suggestions and use inquire for all purposes.  In Old French the Latin in- often became en- and such was the influence on Middle English that the form spread and although English developed a strong tendency to revert to the Latin in-, this wasn’t universal, thus pairs such as enquire/inquire which is why there must always be some sympathy for those learning the language.  There was a native form, which in West Saxon usually appeared as on- (as in the Old English onliehtan (to enlighten)) and some of those verbs survived into Middle English (such as inwrite (to inscribe)) but all are said now to be long extinct.

Enquire or inquire?

Lindsay Lohan says the spelling is "inquiry" so that must be right.

The English word was re-spelled as early as the fourteenth century on the Latin model but the half-Latinized "enquire" has never wholly gone away.  Outside of North America, it's not unknown to come across documents where "inquire" & "enquire" both appear, not in tribute to a particular "rule" of use but just because it hasn't been noticed; it's probably most associated with documents which are partially the product of chunks of texts being "cut and paste".  In the US, where the enquire vs inquire "problem" doesn’t exist because inquire is universal, this must seem a strange and pointless squabble because hearing a sentence like "She enquired when the Court of Inquiry was to hold its hearings" would unambiguously be understood and if written down, there could be no confusion if the spelling forms were to appear in either order.  So,  some hold it would be a fine idea if the rest of the English-speaking world followed the sensible lead of the Americans and stuck to "inquire" but history suggests that’s not going to happen and some suggestions for a convention of use have been offered:

(1) Enquire & enquiry are "formal" words to convey the sense of "ask" whereas inquire & inquiry are used to describe some structured form of investigation (such as a "Court of Inquiry").

(2) Enquire is to be used in informal writing and inquire in formal text.

Neither of those suggestions seem to make as much sense as adopting the US spelling and probably just adds a needless layer to a simple word; enquire and inquire mean the same thing: to ask, to seek information, or to investigate. One is therefore unnecessary and enquire should be retired, simply on the basis the Americans already have and there’s lots of them.  Those who resist should follow the one golden rule which is consistency: whatever convention of use is adopted, exclusively it should be used. 

The ultimate court of inquiry, the Spanish Inquisition and the DDF

The Spanish Inquisition, conducting their inquiries.

The Tribunal del Santo Oficio de la Inquisición (Tribunal of the Holy Office of the Inquisition), known famously as the Inquisición española (Spanish Inquisition) was created in 1478 by the Roman Catholic Monarchs, King Ferdinand II (1452–1516; king of Aragon 1479-1516, king of Castile 1475-1504 (as Ferdinand V)) and Queen Isabella I (1451–1504; queen of Castile 1474-1504, queen of Aragon 1479-1504), its remit the enforcement of orthodox Church doctrine in their kingdoms.  Ostensibly established to combat heresy in Spain (though eventually its remit extended throughout the Spanish Empire), the real purpose was to consolidate the power of the monarchy of the newly unified Spanish kingdom.  Its methods were famously brutish and although many records were lost, it's thought close to two hundred-thousand individuals came to the attention of the Inquisition and as many as five-thousand may have been killed; during the tenure of Castilian Dominican friar Tomás de Torquemada (1420–1498), the first grand inquisitor, it's believed some two-thousand were burned at the stake.  Suppressed first by Joseph-Napoléon Bonaparte (1768–1844; king of Naples (1806–1808) and king of Spain (1808–1813)) in 1808, it was restored by Ferdinand VII (1784–1833; king of Spain 1808 & 1813-1830) in 1814, suppressed in 1820, and restored in 1823.  It was finally abolished in 1834 by the Spanish queen regent María Cristina de Borbón (Maria Christina of the Two Sicilies 1806–1878; queen consort of Spain from 1829-1833 and regent of the Kingdom 1833-1840).  Historians have noted that although the Spanish Inquisition didn't last into the twentieth century, there were more than echoes of its methods & techniques witnessed (on both sides) during the Spanish Civil War (1936-1939).  

Rome certainly understood the need to enforce doctrine and punish heretics but they wanted control of the processes, aware even then some of the excesses were proving to be counter-productive and the imperative was to create a body under the direct jurisdiction of the Holy See.  Formed in 1542, was emerged was an institution which in recent years has had a few instances of what in commerce (and increasingly by governments too) is called "re-branding".  Originally named the Supreme Sacred Congregation of the Roman and Universal Inquisition, between 1908-1965 it was known as the Supreme Sacred Congregation of the Holy Office before becoming Congregation for the Doctrine of the Faith (CDF), its best-known prefect (head) being the the German Cardinal Joseph Ratzinger (1927–2022) who, after serving as Chief Inquisitor between 1982-2005) was elected pope as Benedict XVI, serving until his unusual (though not unprecedented) resignation in 2013 when he decided to be styled pope emeritus, living in a kind of papal granny flat in the Vatican until his death.  In 2022, the institution was re-named the Dicastery for the Doctrine of the Faith (DDF) and despite it all, many continue to refer to it as "The Holy Office" (in public) or "The Inquisition" (in private).  There are now (even when under Cardinal Ratzinger as far as in known) no more torture chambers or burnings at the stake but the DDF remains a significant factional player in curia politics although Vatican watchers have detected a grudging softening in the DDF's expressions of doctrinal rigidity since the election of Pope Francis (b 1936; pope since 2013). 

Corona

Corona (pronounced kuh-roh-nuh)

(1) A white or colored circle or set of concentric circles of light seen around a luminous body.

(2) In meteorology, such a circle or set of circles having a small radius and ranging in color from blue inside to red outside, attributable to the diffraction caused by thin clouds, mist, or sometimes dust (distinguished from halo).

(3) In solar astronomy, a faintly luminous envelope outside of the sun's chromosphere, the inner part consisting of highly ionized elements; also called aureola & aureole.

(4) A long, straight, un-tapered cigar, rounded at the closed end.

(5) In botany, a crown-like appendage, especially one on the inner side of a corolla, as in the narcissus.

(6) In anatomy, the upper portion or crown of a part, as of the head.

(7) In architecture, the projecting, slab-like member of a classical cornice supported by the bed molding or by modillions, dentils, etc., and supporting the cymatium.

(8) The tonsure of a monk or other cleric.

(9) In ecclesiastical dress, a gold-colored stripe around the lower edge of a clerical headdress, as of a miter.

(10) A chandelier of wrought metal, having the form of one or more concentric hoops.

(11) In zoology, the head or upper surface of an animal, such as the body of an echinoid or the disc and arms of a crinoid.

(12) As Coronaviruses, a group of viruses which infect mammals and birds.  In humans, they cause usually mild (including 229E, the common cold) respiratory infections but forms such as SARS, MERS the famous COVID-19 can be lethal.

1555–1565: From the Latin corōna (garland, crown) from the Ancient Greek κορώνη (korṓnē or korōnis (crown, any curved object)), akin to korōnís (wreath; curved, beaked) & kórax (crow; raven); related was the Latin curvus (curved).  A doublet of crown, the plural forms are coronas & coronae.

COVID-19 and Coca-Cola

COVID-19 (an abbreviation of coronavirus disease 2019) was the name of the disease caused by SARS-CoV-2.  The name was adopted in February 2020, chosen by the World Health Organization (WHO) in partnership with the Committee on Taxonomy of Viruses; until then, variously it had been called 2019-nCoV, Novel coronavirus or Wuhan coronavirus.  SARS-CoV-2 is related to MERS-CoV (which causes Middle East respiratory syndrome (MERS)) and SARS-CoV (which causes severe acute respiratory syndrome (SARS)).

The Sun and its corona (left) and a depiction of the SARS-CoV-2 virus (bottom).

The class to which these viruses belong is called corona because, when viewed under an electron microscope, there’s a resemblance to the crown-like corona (the halo or ring of fire) around the Sun, seem when viewed through an appropriate telescope or other device.  The corona around the sun has long been known but viruses have been seen only since the development of the electron microscope because human viruses are very small, typically 100 nanometers (1 metre = 1,000 mm = 1,000,000 micrometres = 1,000,000,000 nanometres).  In the evolutionary timeline of life on earth, it's believed bacteria emerged quite some time before viruses.  Bacteria appear to have been one of the earliest forms of life and, because no evidence of life has yet been detected anywhere else in the universe, they're perhaps among the oldest anywhere.  Single-celled organisms with a relatively simple structure and capable of independent reproduction, bacteria are thought to have appeared some 3.5 to 3.8 billion years ago (the Earth dating back 4.5 billion) and the evidence suggests the viruses emerged 2-3 billions years ago.  Unlike bacteria, viruses are not considered living organisms in the traditional sense because they cannot carry out metabolic processes or reproduce on their own; instead, they are genetic material (DNA or RNA) enclosed in a protein coat.

As far as is known, all life forms now extant (and all extinct forms known) are descended ultimately from the one initial instance; life started once which means humans are related to cats, dogs, trees & bananas as well as to bacteria & viruses.  That makes people, bacteria and just about everything else vulnerable to infection by one virus or another, the consequences ranging from nothing to death but the behavior can also be used to advantage and a certain class of virus, the bacteriophage, after a long period of neglect during the antibiotic era, is attracting new interest.

Some viruses can be helpful: A depiction of bacteriophages phaging.

Not all viruses are bad like SARS-CoV-2.  A bacteriophage, known almost always as a phage, is a virus which infects and replicates within bacteria.  Phages are composites of proteins that surround a DNA or RNA genome and may encode any number of genes from a handful to many hundreds.  Phages replicate within the bacterium following the injection of their genome into the target cytoplasm.  Phages exist naturally in the environment and are among the most common and diverse entities on earth.  Serious research began in several parts of Europe during the late nineteenth century and have been used for almost a century as anti-bacterial agents the former USSR and Central Europe.  In the West, phage therapy (using specific viruses to fight difficult bacterial infections) has been of interest for some time, attention heightened as the problem of antibiotic-resistant bacteria (superbugs in the popular imagination) began to grow in severity (the US Centers for Disease Control and Prevention (CDC) attributes one death every 15 minutes in the US to superbugs).  Since the discovery of penicillin, antibiotics have been used as a reliable cure for those suffering from once lethal bacterial infections but, over decades, a handful (compared with the trillions and trillions killed) of bacteria have proved resistant to antibiotics and as these survivors multiply, new infections emerge.  Historically this had prompted the development of revised or new antibiotics but the biological arms race has reached the point where some infections caused by called antibiotic resistant bacteria cannot be treated and for many other serious infections, the number of potent “last resort” antibiotics is dwindling.

Hence the interest in phages, a type of “friendly virus” which can be weaponized to fight even the most virulent and persistent bacterial infections.  Phages work as well as they do because viruses like the tiresome SARS-Cov-2 that makes humans sick, phages can infect only bacteria and are selective about which they target, a vital aspect of their role in medicine because human survival depends on the billions of bacteria in our bodies.  These phages are far from rare, existing in the natural environment almost everywhere on the planet and scientists conducting research find dirty waterways or damp, aerated, warm, decaying soil (both areas where high bacterial growth might be expected) are good places to collect samples.  The advantages phages offer are well known but there are also drawbacks and indeed some of the features of phages manifest as both.  For example, the great specificity of phages helpful in that they can be administered safely with the knowledge that no other organisms will be harmed but this can be a practical disadvantage in clinical medicine when it’s not known exactly which bacteria need to be targeted, which is why broad-spectrum antibiotics proved so effective at scale.  Being wholly natural, the shelf-life of phages is highly variable and there’s little experience in their administration beyond some communities in Eastern Europe where they’ve been part of medical practice for over a century.  Additionally, bacteria can develop resistance even to phages and one practical impediment to deployment not well recognized until recent years is that compared to chemical molecules, phages are quite big and there are sites in the human body which will be inaccessible.

Electron micrograph of a Coronaviruses in colorized and in grey-scale.

The images captured from electron microscopes are always in black-and-white but are often artificially colored in the post-production process for better visualization and to assist with analysis.  Because of the resolution limit of the optical microscope, even at the highest magnification, viruses couldn’t be seen because their size meant they lay beyond the spectrum of visible light, the range of resolution being limited by the wavelength of the visible light that illuminates the specimen.  It was the resolution of the electron microscope, developed in the early 1930s, and able to offer an illumination with a wavelength much smaller than visible light which first made viruses visible.  An electron has the properties both of a particle and a wave so an electron’s wavelength is determined by its energy (or speed).  If an electron is accelerated to a speed of a million meters per second (circa 2.2 million mph (3.5 million km/h)) the physical wavelength is around one-tenth of a nanometer or about the size of an atom.  This permits an electron microscope to probe the structure of atoms in a crystal and thus see viruses.

Lindsay Lohan taking a 330ml lunch.

In February 2021, at a time when the official number of people with COVID-19 was around 107 million, mathematicians calculated all the COVID-19 causing SARS-COV-2 virus then circulating the planet easily would fit in a single (330ml) Coca-Cola can.  Using a model based on the viral load per currently infected victim (which varies during the duration of the infection), it was estimated there were at the time around two-hundred quadrillion (200 million billion or 2x10¹⁷). SARS-CoV-2 virus particles in the world.  Using that number, knowing the size of the virus, it was possible to calculate the total volume and even after accounting for the distinctive projecting spike proteins meaning the spherical particles will leave gaps when stacked together, the total is still less than the internal volume of the 330 millilitre can.

Two-hundred quadrillion is a really big number, there are said to be about that many grains of sand on the planet, but Sars-CoV-2 particles are really small, around a hundred nanometres (one nanometre is a billionth of a meter) so the radius of Sars-CoV-2 is roughly a thousand times thinner than a human hair.  The mathematicians multiplied the numbers, worked out the wastage of space caused by the troublesome spikes accounted for about a quarter of the total volume and concluded that in February 2021, the volume of SARS-CoV-2 in the world was 160 millilitres.  By mid-2021, cases had almost doubled so by then, either the can would be full or, given the margin of error associated with such calculations, a second can might be required.  The caveat to all this is that the math is based on the official number of infected people and nobody knows what the real is although all agree it will be higher but by what factor is guesswork, reliable data just not available to build a model.  Guesses have been proffered ranged from double to twenty times higher.  Depending on which of those is closest, a six-pack or a carton of cans might be filled.

Rare collector’s item: Lindsay Lohan MH Corona Extra tobacco card #480: US$5.00 on eBay.  Unrelated to this card is the specification of the corona cigars, straight-shaped cigars with rounded tops (the end taken to the lips) and defined by length: a corona about 5½ inches (140 mm) long; a petit corona (or corona chica) about 5 inches (125 mm) long, a tres petit corona about 4½ inches (115 mm) long & a half corona about 3¾ (95 mm) inches long.

The Toyota (Corona) 1600GT

1958 Toyota Corona "Van".

It was the Toyota Corona (1957-2001) which not only established the company in the vital US market but lent respectability to the very idea of the “Japanese car”, that term in the early 1960s not the by-word for quality and reliability it would in subsequent decades become.  Noting the success of the small (by US standards) Volkswagen Beetle and other imports, the company shipped a small number of Coronas to the US in the late 1950s but they were unsuitable for the environment (as indeed were a number of the diminutive European models which lacked the ruggedness of the VW) and interest was minimal, the Corona withdrawn from sale in 1960 although unsold models lingered on the lots for another year.

1966 "shovel-nose" Toyota Corona.

It was the third generation Corona, launched in September 1964 in an array of body styles, which was the Toyota passenger car to achieve international success, including in the US.  It was a thoroughly conventional design (ie mechanically a scaled down US sedan) with a body which was modern, inoffensive and practical although some thought the reverse-slanted nose strange.  It came to be nick-named the “shovel-nose” and proved ahead of its time, adopted in 1972 by Lancia for the Beta and in 1976 it appeared on Ford’s Escort RS2000 before variations of the shape eventually became the default for manufacturers seeking to eke out as much aerodynamic efficiency as possible.

The "shovel-nose" caught on: 1972 Lancia Beta (left) & 1976 Ford Escort RS2000 (right).  

The export range appeared in volume but the most desirable models were reserved for the JDM (Japanese domestic market), a long-standing, industry-wide practice which has had the effect of creating a minor export business for those who can satisfy the demand in markets like Australia, New Zealand & North America for the high-performance versions which have something of a cult-following.  The 1967 1600GT (or GT-5 for those with the optional five-speed gearbox) coupé (for this JDM “halo” model the Corona badge wasn’t used) was modest compared with some of the wild machinery which would appear in subsequent decades but by the standards of its time, there was some genuine sophistication.  The body was the standard two-door hardtop but the centrepiece was a double overhead camshaft (DOHC) cylinder head atop the 1600 cm³ four cylinder engine, the head designed by Yamaha which had also developed the one used on the straight-six in the exotic Toyota 2000 GT sports car made famous by the appearance of a custom built roadster version in the James Bond film You Only Live Twice (1967).

1967 Toyota 2000GT roadster.  Two 2000GT coupés were converted into roadsters for You Only Live Twice (one used for filming, the other a "back-up"), the work undertaken by Toyota’s special Toyopet Service Centre in Tsunashima.  The wire wheels were exclusive to the roadsters (15×5 inch magnesium wheels were used on the coupés) and the pair were very much movie props, neither vehicle fitted with side windows or a soft-top.  The "back-up car" is now on display in the Toyota Automobile Museum.

Known internally as the 9R, the 1600GT engine took a traditionally English approach to increasing power: twin carburetors, big valves and a high-compression ratio, the combination yielding a then impressive 110 horsepower at 6200rpm, the latter number something to note given the crankshaft was supported by only three main bearings.  Still, being a Toyota engine, reliability was solid and no history of bottom-end failure emerged; whether the unusual firing order (1243) had anything to do with this seems not to be discussed anywhere.  To cope with the new-found power, the Corona’s suspension was strengthened with re-calibrated springs and dampers along with two torque rods to locate the back axle.  That improved things but the Japanese manufacturers, although matching the Europeans in power, still had some way to go in achieving their dynamics; the 1600 GT was no cut-price Alfa Romeo.  It was though very well equipped, another lesson Toyota and other Japanese factories would (painfully) teach the West.  Always a low volume model, production of 1600 GTs totalled 2222, the last built late in 1968.

1967 Toyota 1600GT.  They were available also in red and white.

1974 Toyota Corona advertising.

The 1600GT's cult following notwithstanding, it really wasn't representative of the Coronas which went around the world and for decades provided owners and fleets with reliable, if uninspiring transport (very much the Camry of their time).  That made them memorable for many who may have enjoyed the charms of British, French or Italian machinery but found the quirks, oil-leaks, fragility or apparently insoluble issues electrical issues (often described as "gremlins") made ownership tiresome.  Toyota were aware of the advantage their approach (which put a premium on basic engineering and quality control over the finer points of handling and high-speed braking) and their advertising for the Corona in the 1970s said explicitly: "When your heart says Europe but your head says Japan".  People increasingly followed their heads and by 1989 Toyota released the Lexus, proving they were as good at building a Mercedes-Benz as they were at building Toyotas.  It took many attempts for Mercedes-Benz to become (almost) as good at building Toyotas.

Asymmetric

Asymmetric (pronounced a-sim-et-rick)

(1) Not identical on both sides of a central line; unsymmetrical; lacking symmetry.

(2) An asymmetric shape.

(3) In logic or mathematics, holding true of members of a class in one order but not in the opposite order, as in the relation “being an ancestor of”.

(4) In chemistry, having an unsymmetrical arrangement of atoms in a molecule.

(5) In chemistry, noting a carbon atom bonded to four different atoms or groups.

(6) In chemistry (of a polymer), noting an atom or group that is within a polymer chain and is bonded to two different atoms or groups that are external to the chain.

(7) In electrical engineering, of conductors having different conductivities depending on the direction of current flow, as of diodes

(8) In aeronautics, having unequal thrust, as caused by an inoperative engine in a twin-engined aircraft.

(9) In military theory, a conflict where the parties are vastly different in terms of military capacity.  This situation is not in all circumstances disadvantageous to the nominally inferior party.

(10) In gameplay, where different players have different experiences

(11) In cryptography, not involving a mutual exchange of keys between sender a7 receiver.

(12) In set theory, of a relation R on a set S: having the property that for any two elements of S (not necessarily distinct), at least one is not related to the other via R.

1870–1875: The construct was a- + symmetric.  The a- prefix was from the Ancient Greek ἀ- (a-) (ἀν-) (an- if immediately preceding a vowel) and was added to stems to created the sense of "not, without, opposite of".  The prefix is referred to as an alpha privative and is used with stems beginning with consonants (except sometimes “h”); “an-“ is synonymous and is used in front of words that start with vowels and sometimes “h”.  Symmetric was from the Latin symmetria from Ancient Greek συμμετρία (summetría).  Symmetry was from the 1560s in the sense of "relation of parts, proportion", from the sixteenth century French symmétrie and directly from the Latin symmetria, from the Greek symmetria (agreement in dimensions, due proportion, arrangement", from symmetros (having a common measure, even, proportionate), an assimilated form of syn- (together) + metron (measure) from the primitive Indo-European me- (to measure).  The meaning "harmonic arrangement of parts" dates from the 1590s.  The suffix -ic was from the Middle English -ik, from the Old French -ique, from the Latin -icus, from the primitive Indo-European -kos & -ḱos, formed with the i-stem suffix -i- and the adjectival suffix -kos & -ḱos.  The form existed also in Ancient Greek as -ικός (-ikós), in Sanskrit as -इक (-ika) and the Old Church Slavonic as -ъкъ (-ŭkŭ); A doublet of -y.  In European languages, adding -kos to noun stems carried the meaning "characteristic of, like, typical, pertaining to" while on adjectival stems it acted emphatically.  In English it's always been used to form adjectives from nouns with the meaning “of or pertaining to”.  A precise technical use exists in physical chemistry where it's used to denote certain chemical compounds in which a specified chemical element has a higher oxidation number than in the equivalent compound whose name ends in the suffix -ous; (eg sulphuric acid (H₂SO₄) has more oxygen atoms per molecule than sulphurous acid (H₂SO₃).  Asymmetric & asymmetrical are adjectives, asymmetricity, asymmetricality, asymmetricalness & asymmetry are nouns and asymmetrically is an adverb; the noun plural is asymmetries.

The usually symmetrically attired Lindsay Lohan demonstrates the possibilities of asymmetry.

1975 Kawasaki 750 H2 Mach IV.

Manufacturers of triple-cylinder motorcycles traditionally used single (3 into 1) or symmetrical (3 into 2) exhaust systems (although, during the 1970s, Suzuki offered some of their "Ram-Air" models with a bizarre 3 into 4 setup (the centre cylinder’s header bifurcated) but in 1969 Kawasaki adopted an asymmetric addition for one of the memorable machines of the time.  The Kawasaki 500 H1 Mach III had two outlets to the right, one to the left and was a fast, lethally unstable thing which was soon dubbed the "widow maker".  Improvements to the Mach III made it a little more manageable and its successor, the 750 H2 Mach IV was claimed to be better behaved but was faster still and best enjoyed by experts, preferably in a straight line although, with a narrow power band which peaked with a sudden rush, even that could be a challenge.  The Kawasaki triples remain the most charismatic of the Japanese motorcycles but the prototype had been even more intriguing, using an "asymmetric V" with the two outer cylinders upright while the central barrel was at 90^o so, viewed in profile it appeared a conventional 90^o vee engine, the novelty obvious only from other aspects.  There were genuine advantages in cooling and weight distribution but ultimately the complexity was thought unjustified and the project was cancelled when doubts were expressed about market-acceptance. 

1973 Triumph X-75 Hurricane.

Available only during 1972-1973 and produced in small numbers, the Triumph X75 Hurricane was typical of the motorcycles being produced by the British manufacturers which had neglected development and re-investment and consequently were unable adequately to respond to the offerings of the Japanese industry which had done both aplenty.  Whatever their charms, models like the X75 were being rendered obsolescent, some of the underlying technology dating back decades yet, without the capital to invest, this was as good as it got and some of the fudges of the era were worse.  The X-75 was however ahead of its time in one way, it was a “factory special”, a design influenced by what custom shops in the US had been doing as one-offs for customers and in the years ahead, many manufacturers would be attracted by the concept and its healthy profit margins.  The X-75 is remembered also for the distinctive asymmetric stack of three exhaust pipes on the right-hand side a look adopted in the twenty-first century by MV Agusta and others.

1985 Ferrari Testarossa (1984-1991) “monospecchio-monodado”.

Some of Ferrari's early-production Testarossas were fitted with a single high-mounted external mirror, on the left or right depending on the market into which it was sold and although the preferred term was the Italian “monospecchio” (one mirror), in the English speaking-world it was quickly dubbed the “flying mirror" (rendered sometimes in Italian as “specchio volante” (a ordinary wing mirror being a “specchietto laterale esterno”, proving everything sounds better in Italian)).  The unusual placement and blatant asymmetry troubled some and delighted others, the unhappy more disgruntled still if they noticed the vent on right of the front spoiler not being matched by one to the left.  It was there to feed the air-conditioning’s radiator and while such offset singularities are not unusual in cars, many manufacturers create a matching fake as an aesthetic device: Ferrari did not.  The mirror’s curious placement was an unintended consequence of a European Union regulation (and it doubtful many institutions have in a relatively short time created as many regulations of such collective length as the EU) regarding the devices and this was interpreted by the designers as having to provide 100% rearward visibility.  Because of the sheer size of the rear bodywork necessitated by the twin radiators which sat behind the side-strakes (another distinctive Testarossa feature), the elevation was the only way this could be done but it later transpired the interpretation of the law was wrong, a perhaps forgivable mistake given the turgidity of EU legalese.

The Blohm & Voss BV 141

Focke-Wulf Fw 189 Eurl (Owl).

In aircraft, designs have for very good reason (aerodynamics, weight distribution, flying characteristics, ease of manufacture etc) tended to be symmetrical, sometimes as an engineering necessity such as the use of contra-rotating propellers on some twin-engined airframes, a trick to offset the destabilizing effects of the torque when very potent power-plants are fitted.  There has though been the odd bizarre venture into structural asymmetry, one of the most intriguing being the Blohm & Voss BV 141, the most distinctive feature of which was an offset crew-capsule.  The BV 141 was tactical reconnaissance aircraft built in small numbers and used in a desultory manner by the Luftwaffe (the German air force) during World War II (1939-1945) and although it was studied by engineers from many countries with some prototypes built, the layout never entered mainstream use. The origin of the curious craft lay in a specification issued in 1937 by the Reichsluftfahrtministerium (RLM; the German Air Ministry) which called for a single-engine reconnaissance aircraft, optimized for visual observation and, in response, Focke-Wulf responded with their Fw 189 Eurl (Owl) which, because of the then still novel twin-boomed layout, encountered some resistance from the RLM bureaucrats but it found much favor with the Luftwaffe; over the course of the war, some nine-hundred entered service and it was used almost exclusively as the German's standard battlefield reconnaissance aircraft.  In fact, so successful did it prove in this role that the other configurations it was designed to accommodate (liaison and close-support ground-attack) were never pursued.  Although its performance was modest, it was a fine airframe with superb flying qualities and an ability to absorb punishment which, on the Russian front where extensively it was deployed, became famous and captured examples provided Russian aeronautical engineers with ideas which would for years influence their designs.

1982 Ford (Australia) XE Fairmont Ghia 5.8 (351) ESP.  Finding asymmetry in unexpected places brings joy to some and annoys others.

The RLM had also invited Arado to tender but their Ar 198, although featuring an unusual under-slung and elongated cupola which afforded for the observer a uniquely panoramic view, proved unsatisfactory in test-flights and development ceased.  Blohm and Voss hadn't been included in the RLM's invitation but anyway chose to offer a design which was radically different even by the standards of the innovative Fw 189.  The asymmetric BV 141 design was eye-catching with the crew housed in an extensively glazed capsule, offset to starboard of the centre-line with a boom offset to the left which housed the single-engine in front with the tail to the rear.  Prototypes were built as early as 1938 and the Luftwaffe conducted operational trials over both the UK and USSR between 1939-1941 but, despite being satisfactory in most respects, the Bv 141 was hampered by poor performance, a consequence of using an under-powered engine.  A re-design of the structure to accommodate more powerful units was begun but delays in development and the urgent need for the up-rated engines for machines already in production doomed the project and the Bv 141 was in 1943 abandoned.

Blohm & Voss BV 141 prototype with full-width rear elevators & stabilizers.

Production Blohm & Voss BV 141 with port-only rear elevator & stabilizer.

Despite the ungainly appearance, test-pilots reported the Fw 141 was a nicely balanced airframe, the seemingly strange weight distribution well compensated by (1) component placement, (2) the specific lift characteristics of the wing design and (3) the choice of opposite rotational direction for crankshaft and propeller, the torque generated used as a counter-balance.  Nor, despite the expectation of some, were there difficulties in handling whatever behavior was induced by the thrust versus drag asymmetry and pilots all indicated some intuitive trimming was all that was needed to compensate for any induced yaw.  The asymmetry extended even to the tail-plane, the starboard elevator and horizontal stabilizer removed (to afford the tail-gunner a wider field of fire) after the first three prototypes were built; surprisingly, this was said barely to affect the flying characteristics.  Focke-Wolf pursued the concept, a number of design-studies (including a piston & turbojet-engine hybrid) initiated but none progressed beyond the drawing-board.

Asymmetric warfare

In the twenty-first century, the term “asymmetric warfare” became widely used.  The concept describes conflicts in which there are significant disparities in power, capability and strategies between opposing forces and although the phrase has become recently fashionable, the idea is ancient, based often on the successes which could be exploited by small, mobile and agile (often irregular) forces against larger, conventionally assembled formations.  Reports of such tactics are found in accounts of conflicts in Asia, Africa, the Middle East and Europe from as early as reliable written records have been found.  The classic example is what came later to be called “guerrilla warfare”, hit-and-run tactics which probe and attack a weak spots as they are detected, the ancestor of insurgencies, “conventional” modern terrorism and cyber-attacks.  However, even between conventional national militaries there have long been examples of the asymmetric such as the use of small, cheap weapons like torpedo boats and mines which early in the twentieth century proved effective against the big, ruinously expensive Dreadnoughts.  To some extent, the spike in use of the phrase in the post-Cold War era happened because it provided such a contrast between the nuclear weapon states which, although having a capacity to destroy entire countries without having one soldier step foot on their territory, found themselves vulnerable to low-tech, cleverly planned attacks.

Although the term “asymmetric warfare” encompasses a wide vista, one increasingly consistent thread is that it can be a difficult thing for "conventional" military formations to counter insurgencies conducted by irregular combatants who, in many places and for much of the time, are visually indistinguishable from the civilian population.  The difficulty lies not in achieving the desired result (destruction of the enemy) but managing to do so without causing an “excessive” number of civilian causalities; although public disapproval has meant the awful phrase “collateral damage” is now rarely heard, civilians (many of them women & children) continue greatly to suffer in such conflicts, the death toll high.  Thus the critique of the retaliatory strategy of the Israel Defence Force (IDF) in response to the attack by the Hamas on 7 October 2023, Palestinian deaths now claimed to exceed 20,000; that number is unverified and will include an unknown number of Hamas combatants but there is no doubt the percentage of civilian deaths will be high, the total casualty count estimated early in January 2024 at some 60,000.  What the IDF appear to have done is settle on the strategy adopted by Ulysses S Grant (1822–1885; US president 1869-1877) in 1863 when appointed head of the Union armies: the total destruction of the opposing forces.  That decision was a reaction to the realization the previous approach (skirmishes and the temporary taking of enemy territory which was soon re-taken) was ineffectual and war would continue as long as the other side retained even a defensive military capacity.  Grant’s strategy was, in effect: destroy the secessionist army and the secessionist cause dies out.

In the US Civil War (1861-1965) that approach worked though at an appalling cost, the 1860s a period when ballistics had advanced to the point horrific injuries could be inflicted at scale but battlefield medical tools and techniques were barely advanced from Napoleonic times.  The bodies were piled high.  Grant’s success was influential on the development of the US military which eventually evolved into an organization which came to see problems as something not to be solved but overwhelmed by the massive application of force, an attitude which although now refined, permeates from the Pentagon down to platoon level.  As the US proved more than once, the strategy works as long as there’s little concern about “collateral damage”, an example of this approach being when the Sri Lankan military rejected the argument there was “no military solution” to the long running civil war (1983-2009) waged by the Tamil Tigers (the Liberation Tigers of Tamil Eelam (LTTE)).  What “no military solution” means is that a war cannot be won if the rules of war are followed so the government took the decision that if war crimes and crimes against humanity were what was required to win, they would be committed.

In the 1990s, a number of political and military theorists actually advanced the doctrine “give war a chance”, the rationale being that however awful conflicts may be, if allowed to continue to the point where one side gains an unambiguous victory, the dispute is at least resolved and peace can ensue, sometimes for generations.  For most of human history, such was the usual path of war but after the formation of the United Nations (UN) in 1945 things changed, the Security Council the tool of the great powers, all of which (despite their publicity) viewed wars as a part of whatever agenda they were at the time pursuing and depending on this and that, that meant their interests sometimes lay in ending conflicts and sometimes in prolonging them.  In isolation, such an arrangement probably could have worked (albeit with much “collateral damage”) but over the years, a roll-call of nations run by politicians appalled by the consequences of war began to become involved, intervening with peace plans,  offering mediation and urging the UN to deploy “peacekeeping” forces, something which became an international growth industry.  Added to that, for a number of reasons, a proliferation of non-government organizations (NGO) were formed, many of which concerned themselves with relief programmes in conflict zones and while these benefited may civilians, they also had the effect of allowing combatant forces to re-group and re-arm, meaning wars could drag on for a decade or more.

In the dreadful events in Gaza, war is certainly being given a chance and the public position of both the IDF and the Israeli government is that the strategy being pursued is one designed totally “to destroy” not merely the military capacity of Hamas but the organization itself.  Such an idea worked for Grant in the 1860s and, as the Sri Lankan military predicted they would, end-game there was achieved in 2009 on the basis of “total destruction”.  However, Gaza (and the wider Middle East) is a different time & place and even if the IDF succeeds in “neutralizing” the opposing fighters and destroying the now famous network of tunnels and ad-hoc weapons manufacturing centres, it can’t be predicted that Hamas in some form won’t survive and in that case, what seems most likely is that while the asymmetry of nominal capacity between the two sides will be more extreme than before, Hamas is more likely to hone the tactics than shift the objective.  The IDF high command are of course realists and understand there is nothing to suggest “the Hamas problem” can be solved and being practical military types, they know if a problem can’t be solved it must be managed.  In the awful calculations of asymmetric conflict, this means the IDF calculate that while future attacks will happen, the more destructive the response now, the longer will be the interval before the next event.