Benzodiazepine (pronounced ben-zoh-dahy-az-uh-peen)
A
family of chemical compounds used as minor tranquilizers that act against
anxiety and convulsions and produce sedation and muscle relaxation; marketed,
with variations, under a number of brand-names and trademarks such as Diazepam
(Valium) and chlordiazepoxide (Librium).
1934: Word is a chemical construct, from benzo (word-forming element used in chemistry to indicate presence of a benzene ring fused with another ring) + di (from the Ancient Greek δίς (dís) (twice) + az (nitrogen-substituted) + epine (from the French hepta (seven-membered).
Benzodiazepines are a class of therapeutic agents capable of producing a calming, sedative effect and used in the treatment of fear, anxiety, tension, agitation, and related states of mental disturbance. Among the most widely prescribed drugs in the world, the first benzodiazepine was chlordiazepoxide (Librium), followed by a large variety of agents, including diazepam (Valium) and alprazolam (Xanax), each with slightly different properties. Benzodiazepines work by enhancing the action of the neurotransmitter gamma-aminobutyric acid (GABA), which inhibits anxiety by reducing certain nerve-impulse transmissions within the brain.
Before the development of the benzodiazepines, the only available anti-anxiety drugs were the barbiturates and meprobamate and, relative to these, the benzodiazepines had fewer unfavorable side effects and a reduced potential for abuse. The thus quickly became the preferred treatment for anxiety, used also to treat insomnia, general stress, calming muscle spasms and preparing patient for anesthesia or dental surgery. Side effects include sleepiness, drowsiness, reduced alertness, and unsteadiness of gait but benzodiazepines are not lethal even in very large overdoses, having the tendency only to increase the sedative effects of alcohol and other drugs. Dependence may however occur, even in moderate dosages, with withdrawal symptoms observed even after short-term use and for long-term users, almost half may suffer withdrawal symptoms which can take months to subside. As a consequence, some long-term users continue to take the drug not because of persistent anxiety but because the withdrawal symptoms are too unpleasant.
Xanax tablets.
Xanax is the brand name for the drug alprazolam which is a benzodiazepine. It is a prescription medication primarily used to treat anxiety disorders, panic disorders and (more controversially) depression. A fast & short-acting benzodiazepine, Xanax works by enhancing the activity of a neurotransmitter called gamma-aminobutyric acid (GABA), which helps to reduce anxiety and promote relaxation. Xanax is regarded as effective for treating anxiety and related disorders when used as prescribed but can be habit-forming, leading to dependence and addiction. Lindsay Lohan released (or "dropped" in the fashionable parlance) the track Xanax in 2019. With a contribution from Finnish pop star Alma (Alma-Sofia Miettinen; b 1996), the accompanying music video was said to be “a compilation of vignettes of life”, Xanax reported as being inspired by Ms Lohan’s “personal life, including an ex-boyfriend and toxic friends”. Structurally, Xanax was quoted as being based around "an interpolation of" Better Off Alone, by Dutch Eurodance-pop collective Alice Deejay, slowed to a Xanax-appropriate tempo.
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