Mutation

Mutation (pronounced myoo-tey-shuhn)

(1) In biology (also as “break”), a sudden departure from the parent type in one or more heritable characteristics, caused by a change in a gene or a chromosome.

(2) In biology, (also as “sport”), an individual, species, or the like, resulting from such a departure.

(3) The act or process of mutating; change; alteration.

(4) A resultant change or alteration, as in form or nature.

(5) In phonetics (in or of Germanic languages), the umlaut (the assimilatory process whereby a vowel is pronounced more like a following vocoid that is separated by one or more consonants).

(6) In structural linguistics (in or of Celtic languages), syntactically determined morphophonemic phenomena that affect initial sounds of words (the phonetic change in certain initial consonants caused by a preceding word).

(7) An alternative word for “mutant”

(8) In cellular biology & genetics, a change in the chromosomes or genes of a cell which, if occurring in the gametes, can affect the structure and development of all or some of any resultant off-spring; any heritable change of the base-pair sequence of genetic material.

(9) A physical characteristic of an individual resulting from this type of chromosomal change.

(10) In law, the transfer of title of an asset in a register.

(11) In ornithology, one of the collective nouns for the thrush (the more common forms being “hermitage” & “rash”)

1325–1375: From the Middle English mutacioun & mutacion (action or process of changing), from the thirteenth century Old French mutacion and directly from the Latin mūtātion- (stem of mūtātiō) (a changing, alteration, a turn for the worse), noun of action from past-participle stem of mutare (to change), from the primitive Indo-European root mei- (to change, go, move).  The construct can thus be understood as mutat(e) +ion.  Dating from 1818, the verb mutate (to change state or condition, undergo change) was a back-formation from mutation.  It was first used in genetics to mean “undergo mutation” in 1913.  The –ion suffix was from the Middle English -ioun, from the Old French -ion, from the Latin -iō (genitive -iōnis).  It was appended to a perfect passive participle to form a noun of action or process, or the result of an action or process. The use in genetics in the sense of “process whereby heritable changes in DNA arise” dates from 1894 (although the term "DNA" (deoxyribonucleic acid) wasn't used until 1938 the existence of the structure (though not its structural detail) was fist documented in 1869 after the identification of nuclein).  In linguistics, the term “i-mutation” was first used in 1874, following the earlier German form “i-umlaut”, the equivalent in English being “mutation”.  The noun mutagen (agent that causes mutation) was coined in 1946, the construct being muta(tion) + -gen.  The –gen suffix was from the French -gène, from the Ancient Greek -γενής (-genḗs).  It was appended to create a word meaning “a producer of something, or an agent in the production of something” and is familiar in the names of the chemical elements hydrogen, nitrogen, and oxygen.  From mutagen came the derive forms mutagenic, mutagenesis & mutagenize.  Mutation, mutationist & mutationism is a noun, mutability is a noun, mutable & mutant are nouns & adjectives, mutated & mutating are verbs & adjectives, mutational & mutationistic are adjective and mutationally is an adverb; the noun plural is mutations.  For whatever reasons, the adverb mutationistically seems not to exist.

In scientific use the standard abbreviation is mutat and forms such as nonmutation, remutation & unmutational (used both hyphenated and not) are created as required and there is even demutation (used in computer modeling).  In technical use, the number of derived forms is vast, some of which seem to enjoy some functional overlap although in fields like genetics and cellular biology, the need for distinction between fine details of process or consequence presumably is such that the proliferation may continue.  In science and linguistics, the derived forms (used both hyphenated and not) include animutation, antimutation, backmutation, e-mutation, ectomutation, endomutation, epimutation, extramutation, frameshift mutation, hard mutation, heteromutation, homomutation, hypermutation, hypomutation, i-mutation, intermutation, intramutation, intromutation, macromutation, macromutational, megamutation, mesomutation, micromutation, missense mutation, mixed mutation, multimutation, mutationless, mutation pressure, nasal mutation, neomutation, nonsense mutation, oncomutation, paramutation. Pentamutation, phosphomutation. point mutation, postmutation, premutation, radiomutation, retromutation, soft mutation, spirant mutation, stem mutation, stereomutation, ultramutation & vowel mutation.

Ginger, copper, auburn & chestnut are variations on the theme of red-headedness: Ranga Lindsay Lohan demonstrates the possibilities.

Red hair is the result of a mutation in the melanocortin 1 receptor (MC1R) gene responsible for producing the MC1R protein which plays a crucial role also in determining skin-tone. When the MC1R gene is functioning normally, it helps produce eumelanin, a type of melanin that gives hair a dark color.  However, a certain mutation in the MC1R gene leads to the production of pheomelanin which results in red hair.  Individuals with two copies of the mutated MC1R gene (one from each parent) typically have red hair, fair skin, and a higher sensitivity to ultraviolet (UV) light, a genetic variation found most often in those of northern & western European descent.

A mutation is a change in the structure of the genes or chromosomes of an organism and mutations occurring in the reproductive cells (such as an egg or sperm), can be passed from one generation to the next.  It appears most mutations occur in “junk DNA” and the orthodox view is these generally have no discernible effects on the survivability of an organism.  The term junk DNA was coined to describe those portions of an organism's DNA which do not encode proteins and were thought to have no functional purpose (although historically there may have been some).  The large volume of these “non-coding regions” surprised researchers when the numbers emerged because the early theories had predicted they would comprise a much smaller percentage of the genome.  The term junk DNA was intentionally dismissive and reflected the not unreasonable assumption the apparently redundant sequences were mere evolutionary “leftovers” without an extant biological function of any significance.

However, as advances in computing power have enabled the genome further to be explored, it’s been revealed that many of these non-coding regions do fulfil some purpose including: (1) A regulatory function: (the binary regulation of gene expression, influencing when, where, and how genes are turned on or off; (2) As superstructure: (Some regions contribute to the structural integrity of chromosomes (notably telomeres and centromeres); (3) In RNA (ribonucleic acid) molecules: Some non-coding DNA is transcribed into non-coding RNA molecules (such as microRNAs and long non-coding RNAs), which are involved in various cellular processes; (4) Genomic Stability: It’s now clear there are non-coding regions which contribute to the maintenance of genomic stability and the protection of genetic information.  Despite recent advances, the term junk DNA is still in use in mapping but is certainly misleading for those not immersed in the science; other than in slang, in academic use and technical papers, “non-coding DNA” seems now the preferred term and where specific functions have become known, these regions are described thus.

There’s also now some doubt about the early assumptions that of the remaining mutations, the majority have harmful effects and only a minority operate to increase an organism's ability to survive, something of some significance because a mutation which benefits a species may evolve by means of natural selection into a trait shared by some or all members of the species.  However, there have been suggestions the orthodox view was (at least by extent) influenced by the slanting of the research effort towards diseases, syndromes and other undesirable conditions and that an “identification bias” may thus have emerged.  So the state of the science now is that there are harmful & harmless mutations but there are also mutations which may appear to have no substantive effect yet may come to be understood as significant, an idea which was explored in an attempt to understand why some people found to be inflected with a high viral-load of SARS-Cov-2 (the virus causing Covid-19) remained asymptomatic.

In genetics, a mutation is a change in the DNA sequence of an organism and it seems they can occur in any part of the DNA and can vary in size and type.  Most associated with errors during DNA replication, mutations can also be a consequence of viral infection or exposure to certain chemicals or radiation, or as a result of viral infections.  The classification of mutations has in recent years been refined to exist in three categories:

(1) By the Effect on DNA Sequence:  These are listed as Point Mutations which are changes in a single nucleotide and include (1.1) Substitutions in which one base pair is replaced by another, (1.2) Insertions which describe the addition of one or more nucleotide pairs and (1.3) Deletions, the removal of one or more nucleotide pairs.

(2) By the Effect on Protein Sequence: These are listed as: (2.1) Silent Mutations which do not change the amino acid sequence of the protein, (2.2) Missense Mutations in which there is a change one amino acid in the protein, potentially affecting its function, (2.3) Nonsense Mutations which create a premature stop codon, leading to a truncated and usually non-functional protein and (2.4) Frameshift Mutations which result from insertions or deletions that change the reading frame of the gene, often leading to a completely different and non-functional protein.

(3) By the Effect on Phenotype: These are listed as (3.1) Beneficial Mutations which provide some advantage to the organism, (3.2) Neutral Mutations which have no apparent significant effect on the organism's fitness and (3.3) Deleterious Mutations which are harmful to the organism and can cause diseases or other problems.

(4) By the Mechanism of Mutation: These are listed as (4.1) Spontaneous Mutations which occur naturally without any external influence, due often to errors in DNA replication and (4.2) Induced Mutations which result from exposure to mutagens environmental factors such as chemicals or radiation that can cause changes in DNA),

Because of the association with disease, genetic disorders and disruptions to normal biological functions, in the popular imagination mutations are thought undesirable.  They are however a crucial part of the evolutionary process and life on this planet as it now exists would not be possible without the constant process of mutation which has provided the essential genetic diversity within populations and has driven the adaptation and evolution of species.  Although it will probably never be known if life on earth started and died out before beginning the evolutionary chain which endures to this day, as far as is known, everything now alive (an empirically, that means in the entire universe) ultimately has a single common ancestor.  Mutations have played a part in the diversity which followed and of all the species which once have inhabited earth, a tiny fraction remain, the rest extinct.

Nuclear-induced mutations

Especially since the first A-Bombs were used in 1945, the idea of “mutant humans” being created by the fallout from nuclear war or power-plants suffering a meltdown have been a staple for writers of science fiction (SF) and producers of horror movies, the special-effects and CGI (computer generated graphics) crews ever imaginative in their work.  The fictional works are disturbing because radiation-induced human mutations are not common but radiation can cause changes in DNA, leading to mutations and a number of factors determine the likelihood and extent of damage.  The two significant types of radiation are: (1) ionizing radiation which includes X-rays, gamma rays, and particles such as alpha and beta particles.  Ionizing radiation has enough energy to remove tightly bound electrons from atoms, creating ions and directly can damage DNA or create reactive oxygen species that cause indirect damage.  In high doses, ionizing radiation can increase the risk of cancer and genetic mutations and (2) non-ionizing radiation which includes ultraviolet (UV) light, visible light, microwaves, and radiofrequency radiation.  Because this does not possess sufficient energy to ionize atoms or molecules, which there is a risk of damage to DNA (seen most typically in some types of skin cancer), but the risk of deep genetic mutations is much lower than that of ionizing radiation.  The factors influencing the extent of damage include the dose, duration of exposure, the cell type(s) affected, a greater or lesser genetic predisposition and age.

Peter Dutton (b 1970; leader of the opposition and leader of the Australian Liberal Party since May 2022) announces the Liberal Party's new policy advocating the construction of multiple nuclear power-plants in Australia.

The prosthetic used in the digitally-altered image (right) was a discarded proposal for the depiction of Lord Voldemort in the first film version of JK Rowling's (b 1965) series of Harry Potter children's fantasy novels; it used a Janus-like two-faced head.  It's an urban myth Mr Dutton auditioned for the part when the first film was being cast but was rejected as being "too scary".  If ever there's another film, the producers might reconsider and should his career in politics end (God forbid), he could bring to Voldemort the sense of menacing evil the character has never quite achieved. 

Hellraiser (1987) DVD cover (left), Pinhead (centre) and Peter Dutton imagined as Pinhead (right).

However, even if too scary to be a Voldemort, for the next instalment in the Hellraiser franchise, Mr Dutton may be just scary enough to be the next “Pinhead”, the leader of the Cenobites, extra-dimensional, sadomasochistic creatures unable to differentiate between pain and pleasure.  As well, as looking the part, to depict a convincing Cenobite, Mr Dutton would absorb little of the director’s time in rehearsals because he’d need just to “act naturally”.  The first Hellraiser film was released in 1987 and there have since been nine sequels with Pinhead gaining a cult following among aficionados of the genre so, should he need a post-political career, definitely he should audition.  Interestingly, despite many opportunities, Mr Dutton has never denied being a Freemason and that also would work in his favour because it’s clear the Cenobites are a Masonic crew.

On paper, while not without challenges, Australia does enjoy certain advantages in making nuclear part of the energy mix: (1)  With abundant potential further to develop wind and solar generation, the nuclear plants would need only to provide the baseload power required when renewable sources were either inadequate or unavailable; (2) the country would be self-sufficient in raw uranium ore (although it has no enrichment capacity) and (3) the place is vast and geologically stable so in a rational world it would be nominated as the planet's repository of spent nuclear fuel and other waste.  The debate as it unfolds is likely to focus on other matters and nobody images any such plant can in the West be functioning in less than twenty-odd years (the Chinese Communist Party (CCP) gets things done much more quickly) so there's plenty of time to squabble and plenty of people anxious to join in this latest theatre of the culture wars.  Even National Party grandee Barnaby Joyce (b 1967; thrice (between local difficulties) deputy prime minister of Australia 2016-2022) has with alacrity become a champion of all things nuclear (electricity, submarines and probably bombs although, publicly, he seems not to have discussed the latter).  The National Party has never approved of solar panels and wind turbines because they associate them with feminism, seed-eating vegans, homosexuals and other symbols of all which is wrong with modern society.  While in his coal-black heart Mr Joyce's world view probably remains as antediluvian as ever, he can sniff the political wind in a country now beset by wildfires, floods and heatwaves and talks less of the beauty of burning fossil fuels.  Still, in the wake of Mr Dutton's announcement, conspiracy theorists have been trying to make Mr Joyce feel better, suggesting the whole thing is just a piece of subterfuge designed to put a spanner in the works of the transition to renewable energy generation, the idea being to protect the financial positions of those who make much from fossil fuels, these folks being generous donors to party funds and employers of "helpful" retired politicians in lucrative and undemanding roles.

Variation

Variation (pronounced vair-ee-ey-shuhn)

(1) The act, process, or accident of varying in condition, character, or degree; The act of varying; a partial change in the form, position, state, or qualities of a thing.

(2) Amount, rate, extent, or degree of change.

(3) A different form of something; a variant; a related but distinct thing.

(4) In music, the transformation of a melody or theme with changes or elaborations in harmony, rhythm, and melody (the technique often using repetition of material with alterations to melody, harmony, rhythm, timbre, texture, counterpoint or orchestration (though often with some invariant characteristic).

(5) In ballet, a solo dance, especially one a section of a pas de deux.

(6) In astronomy, any deviation from the mean orbit of a heavenly body, especially of a planetary or satellite orbit.

(7) In admiralty use as applied to nautical navigation, the angular difference at the vessel between the direction of true north and magnetic north; also called magnetic declination.

(8) In biology, a difference or deviation in structure or character from others of the same species or group (specifically in genetics the modification of a hereditary trait.

(9) In linguistics, any form of morphophonemic change, such as one involved in inflection, conjugation, or vowel mutation.

(10) In linguistics, when two or more linguistic forms appear in the same environment without a change in meaning, the choice of form being determined by factors of dialect, sociolect, register or simply the speaker's preference.

(11) In board and other games, a a line of play that differs from the original.

(12) In mathematics (variational calculus), an infinitesimal perturbation applied to a function, typically denoted , used to probe how a functional changes.

1350-1400: From the Middle English variation (difference, divergence), from the Middle French variation, from the Old French variacion (variety, diversity) and directly from the Latin variationem & variātiōn (stem of variātiō) (a difference, variation, change), from the past participle stem of variare (to change) (the source of the modern English vary).  The use in the context of musical composition wasn't common until the early nineteenth century.  The available synonyms themselves show an impressive variation: deviation, abnormality, diversity, variety, fluctuation, innovation, divergence, alteration, discrepancy, disparity, mutation, shift, modification, change, swerve, digression, contradistinction, aberration, novelty, diversification, mutation, alteration, difference.  Apart from the English variation, European descendants include the French variation, the Italian variazione, the Portuguese variação, the Russian вариация (variacija), the Spanish variación and Swedish variation.  Variation & variationism are nouns, variationist is a noun & adjective and variational is an adjective; the noun plural is variations.

In jurisdictions of the common law tradition, the word “variation” must be used with caution because while in documents it can be innocuous, it possesses also a number of well-established legal meanings, these varying according to the field of law where applied.  In the broadest (and simplest) sense, a “variation” is a change to an existing legal instrument, obligation, agreement etc that in some way changes something while leaving the arrangement’s whole substantially in existence.  The most familiar use is in contract law, a variation to a contract an agreement between parties to the contract to alter one or more of the terms.  In practice, despite the evolved rules, with the agreement of all parties, a variation to a contract can be so fundamental that it really become a “new contact”.  Provided there is certainty in the wording of the “variation” and all parties are content, this can be uncontroversial but in disputes, a variation can be found to be so fundamental a court will declare it a “new contract”.  Contract variations are so common (and often oral transactions if minor) that most pass unnoticed though disputed variations are among some of the famous entries in contract law text books.  In the jargon, a variation is conceptually distinct from a rescission (terminating an existing contract) or a novation (substituting a new contract or party for an existing one).

The interesting technical aspect of course is the point at which a “variation” becomes a contract, the terminology of significance because just because those writing something call it a “variation”, that doesn’t mean a court will accept it is one; depending on this and that, it may be held what the parties call a “variation” has, in effect, rescinded and replaced the original contract.  Borrowing from the traditions of equity the maxim “equity looks at substance rather than form” and what contract law judges do is look at consequence rather than the label.  One who would have understood that what matters is substance rather than form was comrade Stalin.  He eventually would find the Yugoslavian communists just to troublesome but while they could still be controlled, he was inclined to despair, complaining they were “more Marxist than Marx” and became annoyed with one delegation to which he'd just explained the importance of assuming control of the organs of state without it appearing a communist takeover.  All they wanted to talk about was the design of the red stars for the caps of the police and military personnel, prompting him angrily to exclaim: “What do you want with red stars on your caps?  The form is not important but what is gained, and you—red stars!  By God, there’s no need for stars!”     

Ginger, copper, auburn & chestnut are variations on the theme of red-headedness: Lindsay Lohan demonstrates the possibilities. 

Courts can also impose variations on their own orders (in which a term or terms might be altered but the order remains operative).  A judge of their own volition may issue a variation or it can be a response to a request from one of the parties (or both) to the proceedings.  Variations in orders are very common in family matters (quantum of maintenance payments, shared parenting arrangements etc) and criminal law (a sentence, bail or parole arrangements etc).  As a piece of judicial administration, variations are a vital aspect because, analogous with the use in contract law, they are a “modification”, meaning the force of the original remains afoot with no need for a re-hearing or the making of a new order.  Of course, a court may choose to set aside an order and make a new one; it’s on an order-by-order basis.  In specialized matters such will or trusts, variations can highly be regulated the laws of trusts especially specific and, as Rupert Murdoch (b 1931) found out, sometimes legally bulletproof.  Beneficiaries and trustees are of course subject to restrictions on variations but courts are also governed by the rules.  

Glenn Gould and the Goldberg Variations: 1955 & 1981

Published in 1741, J.S. Bach’s (1685-1750) Goldberg Variations consists of an aria and thirty variations.  Written for the harpsichord, it was named after German harpsichordist & organist Johann Gottlieb Goldberg (1727-1756), thought to have undertaken the first performance.  The work is now part of the canon of Baroque music but, before 1955, was an obscure piece of the Bach repertoire, a technically difficult composition for the hardly fashionable harpsichord and known mostly as a device for teachers to develop students’ keyboard skills.  Even for aficionados of the Baroque, it was rarely performed.

Glenn Gould (1932-1982) was a Canadian classical pianist, his debut album on the then novel twelve-inch vinyl LP an interpretation of The Goldberg Variations, played not on a harpsichord but a piano.  It was at once acknowledged to be an extraordinary performance and although critics don't always embrace radical approaches to older pieces, the praise was almost universal although there was one reviewer wo expressed "shock" ate Gould's fingers moving at a tempo the composer would never have envisioned, resulting in a piece of electrifying intensity; it really was something beyond mere interpretation. As well as introducing him to a wider audience, The Goldberg Variations proved also Gould's swansong, uniquely for him, re-recorded in 1981 and issued days before his death.  Eschewing the stunningly fast pace that had made the earlier recording famous and clearly the work of a mellower, more reflective artist, for those familiar with the original, it’s a masterpiece of controlled tension.  In 2002, Sony re-released both, the earlier essentially untouched, the later benefiting from a re-mastering correcting some of the technical deficiencies that tended to plague many early digital releases.  Although critics and professional musicians doubtlessly understood why Gould believed there were aspects of the 1955 performance that detracted from the whole and why he felt his second attempt the better piece of art, for those who listen to music for pleasure, it’s still the original that thrills.

Rarely can a single recording have so successfully revived a long-neglected work but that’s what Gould’s 1955 release did for Bach’s Goldberg Variations, his audacious interpretation unlocking fascinations that have since drawn audiences although not until the next century were many other pianists tempted into the studio.  The (alleged) early history also is intriguing: When first published, the piece was titled: “Aria with diverse variations for a harpsichord with two manuals.  Composed for Music Lovers to Refresh their Spirits.”  While we can be grateful for the adoption of the punchier “Goldberg Variations”, the origins of the wordy original may lie in the household of an insomniac Russian count then serving as ambassador to the electoral court of Saxony (part of the Holy Roman Empire).  To sooth him to sleep, the ambassador would have the court musician (Johann Gottlieb Goldberg) spend evenings in an antechamber, playing the harpsichord.  It was the count who requested Bach to compose works of a “gentle yet lively character” so that, even if not lulled to sleep, he might be cheered up.  That tale appeared in a very early biography of Bach and few historians think it likely (his pupil Goldberg was the aged 14) but it’s attractive enough not to be forgotten and while the inclusion of “lively” might seem a strange request from an insomniac, as a chronic condition it has been linked to depression.

Simone Dinnerstein, Goldberg Variations by J.S. Bach (Telarc CD-80692).

Additionally, the count may have had scripture in mind:  “And it came to pass, when the evil spirit from God was upon Saul, that David took an harp, and played with his hand: so Saul was refreshed, and was well, and the evil spirit departed from him.” (1 Samuel 16:23; King James Version of the Bible (KJV, 1611).  Not for nothing is Bach known as perhaps the greatest composer of “Church Music”, his works often including what was in his lifetime called gemüths-ergetzende (soul-enhancing).  Certainly, the work retains its capacity to stun, US pianist Simone Dinnerstein’s acclaimed recording in 2007 one of that year’s big hits on the classical charts: Released by Telarc, it was her self-financed project to mark a return to performance after pausing to give birth to her first child and definitely it was not a Gould 1.1 or 2.1.  Preformed on a 1903 Hamburg Steinway model D concert grand, the sound was sumptuous without the contrived lushness many studios once were compelled to concoct in the day before digital techniques were refined to the point where individual notes could be captured almost in the space’s “specific cubic millimetres”.  What’s often forgotten about the Goldberg Variations is that although reviewers have often focused on the “difficult passages”, some of it is simple indeed and it’s this “light & dark” that can be exploited; Gould in 1955 had his approach, Dinnerstein in 2007 had her own and the contrast in obvious from the opening aria, played at a tempo that will seem startling to those who have only heard Gould’s first take on the meditation.  What she seems to have decided is it could be a romantic piece (not the most fashionable view in 2007), not from beginning to end, but with the character of those passages gaining emphasis from the more rapid sections.  It was an accomplished work and while the virtuosity might have been expected, it’s the inventiveness that will intrigue although there will be some who expected more, some of the repeats not included, presumably a technical limitation of the single-CD release.  Hopefully, like Gould, she’ll re-record, now technology no longer imposes such constraints.

Fringe

Fringe (pronounced frinj)

(1) A decorative border of thread, cord, or the like, usually hanging loosely from a raveled edge or separate strip; an edging consisting of hanging threads, tassels etc.

(2) In architecture, engineering, gardening, interior decorating etc, anything resembling or suggesting this (sometimes used loosely).

(3) An outer edge; margin; the periphery.

(4) In political science, something regarded as peripheral, marginal, secondary, or extreme in relation to something else; Those members of a political party, or any social group, holding unorthodox views (famously as the “lunatic fringe”).

(5) In optical physics, one of the alternate light and dark bands produced by the diffraction or interference of light.

(6) In tax law, as “fringe benefit”, a non-cash element of earning treated as income for taxation purposes (sometimes at a concessional rate).

(7) To furnish with or as if with a fringe; to serve as a fringe for, or to be arranged around or along so as to suggest a fringe; to be a fringe.

(8) In hairdressing, a style in which hair sits vertically across the forehead (synonymous with “bangs”, the predominant US form although the latter describes a wider range of cuts and, under the influence of social media, is now widely used).

(9) In botany, the peristome or fringe-like appendage of the capsules of most mosses.

(10) In structured performance art, a series of events conducted in parallel with (though not formerly a part of) an established festival (Edinburgh Fringe; Adelaide Fringe etc).

1325–1375: From the Middle English frenge (ornamental bordering; material for a fringe), from the Old French frenge (thread, strand, fringe, hem, border) (which endures in Modern French as frange), from the Vulgar Latin frimbia (a metathetic variant of the Late Latin plural fimbria (fibers, threads, fringe)), from the Latin fimbriae (fringe) of uncertain origin.  It was related to the German Franse and Danish frynse and came to replace the native Middle English fnæd (fringe), byrd (fringe) & fasel (fringe) from the Old English fæs (fringe) & fnæs (fringe).  As a verb which described “to decorate with a fringe or fringes”, use emerged in the mid-fifteenth century.  The meaning “a border, a boundary, an edge” dates from the 1640s while the figurative sense of “an outer edge, the margin” didn’t come into use until the 1890s although fringe had been an adjective since 1809.  The use of the technical term “fringe benefits” was first recorded in 1952.  Fringe is a noun, verb & adjective, fringed & fringing are verbs and fringeless, fringelike & fringy are adjectives; the noun plural is fringes.

For those seeking an example of the fecundity of the human imagination, Urban Dictionary has a listing of their contributors' suggestions in which fringe is an element including: mini-fringe, fringe fries, Tetris fringe, stoner fringe, wannabe fringe, minge fringe, vagina fringe, fringe of wisdom, fringe sex, clunge fringe, stu fringe, fringed purse, fringe flicker, pube fringe, fringe binge, fanny fringe, block fringe, fringed unicorn, fringe wizzle, chocolate fringe, box fringe, fringe of darkness, fringe sleeper, fucking fringe & grunge fringe.  Especially in those with some anatomical reference, there may be some overlap in meaning but it remains an impressive list.

Slides from the research which identified the Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe gene (now called LFNG), an an essential mediator of somite segmentation and patterning.

In the science of genetics, “lunatic fringe” was too tempting to resist. As in many fields in science, the privilege of allocating a name for a gene is granted to whomever discovered it and those working on fruit flies and other creatures concocted, inter alia: Tinman (fruit flies with a mutated Tinman gene do not develop a heart); Casanova (Zebrafish with a mutation in the Casanova gene develops two hearts); INDY (I’m not dead yet (a reference to a line in the film Monty Python and the Holy Grail) a mutation in the INDY gene prolongs the lifespan of fruit flies; Cheap Date (fruit flies with a mutation in the Cheap Date gene become highly sensitive to alcohol); Dracula (Zebrafish with a mutated Dracula gene are hyper-sensitive to light and soon die; Sonic Hedgehog (Fruit fly embryos with mutated Sonic hedgehog gene develop spikes that resembles a hedgehog); Pinhead (a fruit fly gene which resembled humans colloquially called "pinheads"); Groucho Marx (a gene in metazoa that induces excess facial bristles); Ken & Barbie (Mutations in Ken and Barbie result in fruit flies without external genitalia; Grim & Reaper (the genes Grim & Reaper regulate the death process (apoptosis) in fruit flies).  Even the names of some of genes discovered in fruit fly (and other non-human) research proved to be controversial because so many were shared with humans and accordingly the Human Genome Organization’s (HUGO) gene naming committee was petitioned to change them.   As part of this linguistic sanitization, three christened during the decoding of the human genome (Lunatic Fringe, Manic Fringe & Radical Fringe) were anonymized respectively as LFNG, MFNG & RFNG.

Lunatic Fringe, Canterbury, England.

In parts of the English-speaking world, it’s not uncommon to find a hairdressing salon called Lunatic Fringe but it’s less common in North America where the preferred term for what in the UK, Australia etc was traditionally called a fringe, is “bangs”.  Under the influence of social media and other cultural exports, the Americanism has spread and bangs is now commonly heard everywhere and it’s proved technically useful for professional hairdressers who often distinguish between the classic fringe and a variety of cuts called bangs (which might be considered partial fringes), typically a cut which involves some strands cut short in front of the face or longer, usually thicker strands at the sides to “frame the face”.  The origin of the use of “bangs” in this context is mysterious, some claiming it was a clipping of the hairdresser’s phrase “bang off” which meant to cut the hair in front of the face short, straight & even while others suggest a link with “bang tail”, a dressage cut done to horsetails for equestrian events where the tail hairs would be cut straight across.

Lindsay Lohan with fringe cut with the alluring “dangling in the eyes” look, known as early as 1875 as "the lunatic fringe" (left), in costume as Cleopatra in Liz & Dick (2012) with straight cut fringe (centre) and with curtain bangs which are layered but not quite a bottleneck (right).

There is art & science associated with bangs because not all variations suit all face shapes and certainly aren’t suitable (or even technically possible) with all types of hair.  Additionally, some really work only if complementary makeup is applied but the core base for the decision is almost always the shape of the face, particularly the curve of the jaw-line and essentially they pivot from four points: above the brows, at eye level, at cheekbone level and at the jaw-line.  As a general principle, the hairdresser’s four point rule for bangs is (1) square or heart-shaped faces look best with something wispier or feathered fringe to add softness, (2) oblong face shapes work well with blunt-cut bangs, (3) round faces can gain the effect of elongation with side-swept or curtain bangs and (4) oval-shaped faces will usually accommodate any bang.  In the jargon of professionals there are curtain bangs, bottleneck bangs, blunt bangs, curly bangs, side-swept bangs, layered bangs, choppy bangs, braided bangs, wispy bangs, wavy bangs, micro bangs, shaggy bangs, piecey bangs, JBF bangs & clip-in bangs.

Ali Lohan (b 1993) photographed with her pregnant sister wearing Sandal-Malvina Fringe Tank Dress (left).  The shoes are Alexandre Birmen Clarita Platforms although, as the pregnancy progresses, the Instagram feed can be expected increasingly to feature sensible and comfortable footwear such as Nike’s Air Vapormax Multicolor sneakers (right).

Fringe “festivals” (Edinburgh Fringe; Adelaide Fringe etc).are events which “piggy-back” on mainstream “official” events (Edinburgh Festival; Adelaide Festival etc).  They began as “pirate events” but often became so popular they really came to be considered part of the event and schedules of both came to be designed in conjunction.  The notion of them being “fringe” referenced (1) their components being exhibited or preformed not in the main performance spaces but in places on the periphery and (2) their content being (allegedly) avant-garde (“edgy” in arty talk) or too controversial to be staged in the main event.

Theodore Roosevelt in fringed jacket with Winchester Model 1876, customized with a half-round octagonal barrel, pistol grip, deluxe checkered wood, case-hardened receiver and a shotgun-style butt.

The “lunatic fringe” is really not a phrase from political science (although not a few academics seem to enjoy using it); and in this context it was coined by a politician and is a favorite in popular journalism.  Although many dictionaries early in the twentieth century are said to have described “lunatic fringe” as “a splendidly prejudicial British phrase, with its suggestion of hair dragged villainously low over the forehead or edging the circumference of the face in the way that magistrates disapprove of”, it seems first to have been used of political matters by Theodore Roosevelt (1858–1919; US president 1901-1909) in a letter to Senator Henry Cabot Lodge (1850–1924) on 4 November 1913.   In the letter, he wrote: “I have got some very amusing letters from the lunatic fringe. . . . It is extraordinary how they take hold of people who are just a little mad themselves.”

Thereafter, the phrase became widely known and has since been used of extremist groups or individuals with radical or unconventional views.  It’s in a sense a successor to the way “ultra” was earlier used (ultimately as both noun and adjective) as a prefix (ultra-Tory, ultra-revolutionary etc) before emerging in its own right as a “curtailed word”.  In modern use, it’s handy in that it’s politically agnostic: Donald Trump (b 1946; US president 2017-2021) could say of his Democratic Party challenger, Joe Biden (b 1942; US president since 2021) that he was “…a candidate that will destroy this country and he may not do it himself. He will be run by a radical fringe group of lunatics that will destroy our country” as effortlessly as earlier Barack Obama (b 1961; US president 2009-2017) could describe the Republican Party’s Tea Party faction as “… a lunatic fringe which the Republican leadership should reign in or else the country would suffer.”  However, although President Roosevelt may have thought he was coining something original, some forty years earlier the phrase had some currency among hairdressers in West Virginia, the Wheeling Daily Register in July 1875 reporting “…lunatic fringe is the name given to the fashion of cropping the hair and letting the ends hang down over the forehead.”

Lindsay Lohan with "lunatic fringe" (left), a lion (centre) in China's Guangzhou Zoo with fringe-cut said to be induced by "high humidity" and a piece (right) by Miguel Castro Freitas from his first collection for Mugler, Paris Fashion Week, October, 2025.

In May 2022, a woman visiting Guangzhou Zoo in China was so taken by the sight of a lion’s mane she posted images to her Xiaohongshu (Little Red Book) page.  Xiaohongshu is a Chinese social network and is most often compared with Instagram although the e-commerce focus does seem more overt.  Her posts of the impressively coiffed big cat wasn’t immediately deleted so it may be assumed the CCP (Chinese Communist Party) didn’t deem them a threat to national security.  The lion’s look was so obviously untypical the Xiaohongshu user must have assumed the zoo-keepers were student’s of Lindsay Lohan’s hair styles and speculated, possibly on the basis of her own experience, that “…cutting alone is not sufficient to achieve this look, which would need a combination of washing, cutting, and blow-drying to have this effect.”  Comments on her post mused either the lion was “very docile” or the zoo-keepers were “particularly gutsy”.  Noting the interest, the Guangdong media outlet Viral Press requested a comment from the zoo which issued a statement confirming “…the hairstyle was purely nature’s magic” and a product of “recent days of “high humidity in Guangzhou.”

A fragment from Fashion Feed’s take on Paris Fashion Week, 2025.

Miguel Castro Freitas’s (b 1980) first collection for Mugler was called “Stardust Aphrodite” and the designer described the pieces as “a trilogy of glorified clichés”, the three elements being (1) oversize and bulky, with big fluffy fabrics or shoulder pads, (2) severely tailored with extreme hourglass figures or (3) lightweight, sheer dresses; critics detected some overlap in the use of the motifs.  Although there were a number of nods to Mugler’s historic use of materials in bulk for dramatic effect, the collection otherwise tended to the “less”, one eye catching piece a gown with sparkly silver stars, its straps hung from bare-breasted nipple piercings.  To re-assure those whose toes had curled, critics noted that one was made from “a very lightweight fabric”.  The technique had be seen before, a “nipple grown” the best-remembered thing from the catwalk from one of Mugler’s shows in 1998 and this year’s model was an acknowledged homage but apart from that, it certainly was on-theme, Victoria’s Secret unlikely to see much business generated from those taken with Stardust Aphrodite.

Atavism

Atavism (pronounced at-uh-viz-uhm)

(1) In biology (most often in zoology & botany), the reappearance in an individual of characteristics of some (typically) remote ancestor which have not manifested in intervening generations.

(2) An individual embodying such a reversion.

(3) Reversion to an earlier or more primitive type (a “throwback” in the vernacular).

(4) In sociology and political science, the recurrence or reversion to a past behavior, method, characteristic or style after a long period of absence, used especially of a reversion to violence.

1825-1830: The construct was the Latin atav(us) (great-great-great grandfather; remote ancestor, forefather” (the construct being at- (akin to atta (familiar name for a father) and used perhaps to suggest “beyond”)  + avus (grandfather, ancestor) + -ism.  The –ism suffix was from the Ancient Greek ισμός (ismós) & -isma noun suffixes, often directly, sometimes through the Latin –ismus & isma (from where English picked up ize) and sometimes through the French –isme or the German –ismus, all ultimately from the Ancient Greek (where it tended more specifically to express a finished act or thing done).  It appeared in loanwords from Greek, where it was used to form abstract nouns of action, state, condition or doctrine from verbs and on this model, was used as a productive suffix in the formation of nouns denoting action or practice, state or condition, principles, doctrines, a usage or characteristic, devotion or adherence (criticism; barbarism; Darwinism; despotism; plagiarism; realism; witticism etc).  Atavism & atavist are nouns, atavic, atavistic & atavistical are adjectives and atavistically is an adverb; the noun plural is atavisms.

The primitive Indo-European awo meant “adult male relative other than the father”, the most obvious descendent the modern “uncle”.  The English form was influenced by the French atavisme (the coining attributed usually to the botanist Antoine Nicolas Duchesne (1747-1827 Paris) and was first used in biology in the sense of “reversion by influence of heredity to ancestral characteristics, resemblance of a given organism to some remote ancestor, return to an early or original type”.  The adjective atavistic (pertaining to atavism) appeared in 1847, joined three year later by the now rare atavic (pertaining to a remote ancestor, exhibiting atavism).  Atavism (and its related forms) are none of those words which can be used as a neutral descriptor (notably in botany) or to denote something positive or negative.  Although the core meaning is always some “past or ancestral characteristic”, it tends to be pejorative if use of people or human cultures reverting to some “primitive characteristics” (especially if they be war or other forms of violence.  In the vernacular, the earthier “throwback” has been more common than the rather formal “atavistic” although the circumlocution “skip a generation” is often used for traits that occur after a generation of absence and “throwback” anyway became a “loaded” term because of its association with race (in the sense of skin-color).

Medicine has constructed its own jargon associated with the phenomenon in which an inherited condition appears to “skip a generation”: it’s described often as “autosomal recessive inheritance” or “incomplete penetrance”.  While the phrase “skipping a generation” is not uncommon in informal use, the actual mechanisms depend on the genetic inheritance pattern of the condition.  Autosomal Recessive Inheritance is defined as a “condition is caused by mutations in both copies of a specific gene” (one inherited from each parent).  This can manifest as an individual inheriting only one mutated copy (which means they will be a carrier but will remain asymptomatic) but if two carriers have issue, there is (1) a 25% chance the offspring will inherit both mutated copies and express the condition, (2) a 50% chance the offspring will be a carrier and (3) a 25% chance the offspring will inherit no mutations.  Thus, the condition may appear (and for practical purposes does) skip a generation in those cases where no symptoms exist; the classic examples include sickle cell anemia and cystic fibrosis.  Incomplete Penetrance occurs when an individual inherits a gene mutation which creates in them a genetic predisposition to a condition but symptoms do not develop because of environmental factors, other genetic influences or “mere chance” (and in the matter of diseases like those classified as “cancer”, the influence of what might be called “bad luck” is still probably underestimated, and certainly not yet statistically measured.  In such cases, the mutation may be passed to the next generation, where it might manifest, giving the appearance of skipping a generation and the BRCA1 & BRCA2 mutations for (hereditary) breast cancer are well-known examples.

Lindsay Lohan and her lawyer in court, Los Angeles, December, 2011.

In political science, “atavism” is used to refer to a reversion to older, more “primitive” means of furthering political ends.  Although it’s most associated with a critique of violence, political systems, ideologies, behaviors or economic policies have all be described as “atavistic” and their manifestation is linked often with ideas presented as representing (and implicitly offering a return to) a perceived “golden age”, a past structure which is idealized; it appear often as a reaction to change, notably modernity, globalization, or what is claimed to be a “decline in values”.  Political scientists identify stands in nominally non-violent atavism including: (1) Nostalgic Nationalism.  Nationalist movements are almost always race-based (in the sense of longing for a return to a “pure” ethnicity in which a population is “untainted” by ethnic diversity.  It’s usually a romanticization of a nation's past (historically, “purity” was less common than some like to believe) offering the hope of a return to traditional values, cultural practices, or forms of governance.  (2) Tribalism and Identity Politics. A call to primordial loyalties (such as ethnic or tribal identities), over modern, pluralistic, or institutional frameworks has been a feature of recent decades and was the trigger for the wars in the Balkans during the 1990s, the conflict which introduced to the language the euphemism “ethnic cleansing”, a very atavistic concept.  Tribalism and identity politics depends on group identities & allegiance overshadowing any broader civic or national unity on the basis of overturning an artificial (and often imposed) structure and returning to a pre-modern arrangement. (3) Anti-modernism or Anti-globalization. These are political threads which sound “recent” but both have roots which stretch back at least to the nineteenth century and Pius IX’s (1792–1878; pope 1846-1878) Syllabus Errorum (Syllabus of Errors, 1864) was one famous list of objections to change.  The strategy behind such atavism may be identifiably constant but tactics can vary and there’s often a surprising degree of overlap in the messaging of populists from the notional right & left which is hardly surprising given that in the last ten years both Donald Trump (b 1946; US president 2017-2021; president elect 2024) and Bernie Sanders (b 1941; senior US senator (Independent, Vermont) since 2007) honed their messaging to appeal to the same disgruntled mass.

Elizabeth Boody Schumpeter (1898-1953, left) & Joseph Schumpeter (1883–1950, right).  It was his third marriage.

Austrian political economist Joseph Schumpeter used the word “atavism” in his analysis of the dynamics which contributed to the outbreak of World War I (1914-1918), something he attributed to the old, autocratic regimes of Central and Eastern Europe “dragging the modern, liberal West” back in time.  Schumpeter believed that if commercial ties created interdependence between nations then armed conflict would become unthinkable and US author Thomas Friedman (b 1953) in The Lexus and the Olive Tree: Understanding Globalization (1999) suggested the atavistic tendency of man to go to war could be overcome by modern commerce making connectivity between economies so essential to the well-being of citizens that no longer would they permit war because such a thing would be so dangerous for the economy; it was an attractive argument because we have long since ceased to be citizens and are merely economic units.  Friedman’s theory didn’t actually depend on his earlier phrase which suggested: “…countries with McDonalds outlets don’t go to war with each other” but that was how readers treated it.  Technically, it was a bit of a gray area (Friedman treated the earlier US invasion of Panama (1989) as a police action) but the thesis was anyway soon disproved in the Balkans.  Now, Schumpeter and Friedman seem to be cited most often in pieces disproving their theses and atavism remains alive and kicking.