Poison & Venom

Poison (pronounced poi-zuhn)

(1) A substance with an inherent property that can impair function, cause structural damage, or otherwise injure or destroy life or impair health.

(2) Something harmful or pernicious, as to happiness or well-being.

(3) A slang term for alcoholic liquor.

(4) To administer poison to (a something living).

(5) To ruin, vitiate, or corrupt.

(6) In chemistry, a substance that retards a chemical reaction or destroys or inhibits the activity of a catalyst or enzyme).

(7) In nuclear physics, a substance that absorbs neutrons in a nuclear reactor and thus slows down the reaction.  It may be added deliberately or formed during fission

1200-1250: From the Middle English poisoun, poyson, poysone, puyson & puisun (a deadly potion or substance (and figuratively, "spiritually corrupting ideas; evil intentions,"), from the twelfth century Old French poison & puison (drink, especially a "medical drink" (later "a (magic) potion; a poisonous drink"), from the Latin potionem (nominative potio) (a drinking, a drink) (and also "a poisonous drink"), from potare (to drink), from the primitive Indo-European root poi- & po- (to drink).  The earliest Lastin forms were pōtiōn (drink, a draught, a poisonous draught, a potion), from pōtō (I drink) & pōtāre (to drink).   The Middle English forms displaced the native Old English ator.  The Latin pōtiōn is the stem of pōtiō, the derive forms being pōtio & pōtiōnis.

The evolution from Latin to French followed the pattern of other words (eg raison from rationem), the Latin word also the source of Old Spanish pozon, the Italian pozione and the Spanish pocion.  The modern and more typical Indo-European word for this is represented in English by virus and the slang sense of "alcoholic drink" is an Americanism dating from 1805.  Figurative use was first noted in the late fifteenth century although it appears not to have been applied to persons until 1910.  It was used as an adjective from the 1520s; with plant names from the eighteenth century.  Poison ivy first recorded 1784; poison oak in 1743, poison in 1915.  Poison-pen, the trolling of the time, was popularized 1913 by a notorious criminal case in Pennsylvania although the phrase dates from 1898.

The sense evolution was from "drink" to "deadly drink".  In some Germanic languages "poison" is aligned with the English gift (eg the Old High German gift, the German Gift, the Danish & Swedish gift and the Dutch gift & vergift).  This shift may have been partly euphemistic and partly the influence of the Greek dosis (a portion prescribed (literally "a giving")), used by Greek physicians to mean "a quantum of medicine".  Of persons detested or regarded as exerting baleful influence, poison and poisonous were in use by 1910 while the slang meaning "alcoholic drink" recorded as an an early nineteenth century invention of American English (as in "what's your poison?"); potus as a past-participle adjective in Latin meant "drunken".  The verb in the sense of "to poison, to give poison to" dates from the circa 1300 poisonen, from the Old French poisonner (to give to drink) and directly from the noun poison.  The figurative use in the sense of "to corrupt" emerged in the late fourteenth century.

Venom (pronounced ven-uhm)

(1) The poisonous fluid that some animals, as certain snakes and spiders, secrete and introduce into the bodies of their victims by biting, stinging etc.

(2) Something resembling or suggesting poison in its effect; spite; malice.

(3) Poison in general (inaccurate, now archaic).

(4) To make venomous; envenom (archaic).

(5) Malice, spite.

1175–1225: A variant of the Middle English venim & venym (poison secreted by some animals and transferred by biting) from the Anglo-Norman & Old French venim, venin (poison; malice), from the Vulgar Latin venīmen (source also of the Italian veleno and the Spanish veneno), from the Latin venēnum (magical herb or potion, poison (and in pre-Classical times "drug, medical potion" also "charm, seduction" probably originally "love potion")).  Root was the Proto-Italic weneznom (lust, desire), from the primitive Indo-European wenh (to strive, wish, love) from wen (to desire; to strive for).  Related are the Sanskrit वनति (vanati) (gain, wish, erotic lust) and the Latin Venus.   The variously deformations in post-Latin languages happened apparently by process of dissimilation.  The modern spelling in English was common by the late fourteenth century and the meaning "bitter, virulent feeling or language" dates from circa 1300.

Not interchangeable

A blue Pit Viper.

Poison and venom are often used interchangeably because once in the body, the chemicals can do similar damage, attacking the heart, brain or other vital organs but the meanings are different.  That said, there are many venoms which can be ingested without ill-effect because they are dangerous only if entering the bloodstream although that can happen through a minor cut in the mouth so the practice is not without risk.  Traditionally, venomous creatures bite, sting or stab their victims whereas for poisonous organisms to affect the living, they have to be bitten, inhaled or touched.  The venomous thus need a way in, like fangs or teeth.  The useful rule is if one bites something and one dies, what one bit contained poison; if something bites one and one dies, one was bitten by something venomous.

In late 2017, while on holiday in Thailand, Lindsay Lohan was bitten by a snake.  The creature was presumably not venomous, Lindsay Lohan surviving unaffected but there was no word on the fate of the snake.

Virus

Virus (pronounced vahy-ruhs)

(1) An sub- or ultra-microscopic (20 to 300 nm diameter), metabolically inert, non-cellular infectious agent that replicates only within the cells of living hosts, mainly bacteria, plants, and animals: composed of an RNA or DNA core, a protein coat, and, in more complex types, a surrounding envelope.  Because viruses are unable to replicate without a host cell, they are not considered living organisms in conventional taxonomic systems (though often referred to as live (in the sense of active) when replicating and causing disease.

(2) A quantity of such infectious agents.

(3) In informal use, metonymically, A disease caused by such an infectious agent; a viral illness.

(4) Venom, as produced by a poisonous animal etc (extinct in this context). 

(5) Figuratively, any malicious or dangerous entity that spreads from one place or person to another; a corrupting influence on morals or the intellect. 

(6) In computing, a segment of often self-replicating code furtively planted in a computer program, either to damage a system or for financial gain by a variety of fraudulent techniques.

(7) In computing (loosely used), any form of malware.

Late 1300s: From the Middle English virus (poisonous substance (this meaning now extinct in this context)), from the Latin vīrus (slime; venom; poisonous liquid; sap of plants; slimy liquid; a potent juice), from rhotacism from the Proto-Italic weisos & wisós (fluidity, slime, poison) probably from the primitive Indo-European root ueis & wisós (fluidity, slime, poison (though it may originally have meant “to melt away, to flow”), used of foul or malodorous fluids, but in some languages limited to the specific sense of "poisonous fluid") which was the source also of the Sanskrit visam (venom, poison) & visah (poisonous), the Avestan vish- (poison), the Latin viscum (sticky substance, birdlime), the Greek ios (poison) & ixos (mistletoe, birdlime), the Old Church Slavonic višnja (cherry), the Old Irish fi (poison) and the Welsh gwy (poison).  It was related also to the Old English wāse (marsh).  Virus is a noun & a (rare) verb and viral is an adjective; the noun plural is viruses.

The original meaning, "poisonous substance”, emerged in the late fourteenth century and was an inheritance from the Latin virus (poison, sap of plants, slimy liquid, a potent juice) from the Proto-Italic weis-o-(s-) (poison), probably from the primitive Indo-European root ueis-, thought originally to mean "to melt away, to flow" and used of foul or malodorous fluids, but with specialization in some languages to mean "poisonous fluid".  It’s the source of the Sanskrit visam (venom, poison) & visah (poisonous), the Avestan vish- (poison), the Latin viscum (sticky substance; birdlime) the Greek ios (poison) & ixos (mistletoe, birdlime), the Old Church Slavonic višnja (cherry). The Old Irish fi (poison) and the Welsh gwy (poison).  The meaning "agent that causes infectious disease" emerged in the 1790s, the medical literature of the time describing their manifestation in  especially disgusting terms (the word pus most frequent) and one dictionary entry of 1770 contains the memorable: "a kind of watery stinking matter, which issues out of ulcers, being endued with eating and malignant qualities".  As early as 1728 (borrowing from the earlier sense of "poison"), it had been used in reference to venereal disease, the first recognizably modern scientific use dating from the 1880s.  The first known citation in the context of computing was by Gregory Benford (b 1941) who published The Scarred Man (1970) although it’s often credited to David Gerrold (b 1944), who used the word in this context in When HARLIE Was One (1972).

Before the internet: ARPANET network schematic 1973.

In computing, theoretical work on the self-replicating code (which is the core of a digital virus) was published as early as 1971 and what’s regarded as the first object to behave like a virus (though technically, it would now be called a worm) was released as a harmless amusement on ARPANET (Advanced Research Projects Agency Network) (ARPANET), the internet’s precursor network.  It was called “creeper, catch me if you can!" and, perhaps predictably, other nerds rose to the challenge and release the “reaper” their own worm which killed whatever creepers it found.  Creeper & reaper conducted their cat & mouse game on Digital Equipment Corporation's (DEC) PDP-10, predecessor to the famous PDP-11 mini-computer and at this point, viruses were genuinely harmless (if time wasting) activities conducted between consenting nerds in the privacy of their parochial networks.  However, it was the development of the personal computer (PC) from 1975 and especially the subsequent adoption by business of the IBM-PC-1 (1981) and its clones which created the population in which viruses could spread and while relatively harmless creations like Stoned (1987) tended to amuse because they did little more that display on the screen of an infected device the message "Your PC is now Stoned", there were many others which were quite destructive.  The first which came to wide public attention was probably Melissa (1999) which caused much economic loss and the discussion of which (by mostly male writers in the specialist press) excited some criticism from feminists who objected to headlines like "Melissa was really loose, and boy did she get around".    

The late John McAfee (1945–2021) who led an interesting life.

In medicine, the first antivirus was available in 1903, an equivalent (shrink-wrap) product for computers apparently first offered for sale in 1987 although there seems no agreement of which of three authors (Paul Mace, Andreas Lüning & the late John McAfee) reached the market first.  The adjective viral (of the nature of, or caused by, a virus) dates from 1944 as applied in medicine whereas the now equally familiar, post world-wide-web sense of stuff "become suddenly popular through internet sharing" is attested by 1999 although most seem convinced it must have been in use prior to this.

The rhinovirus (one of a group of viruses that includes those which cause many common colds) was first described in 1961, the construct being rhino- (from the Ancient Greek rhino (a combining form of rhis (nose) of uncertain origin) + virus.  The noun virology appeared in 1935 to describe the then novel branch of science and parvovirus (a very small virus), the construct being parvi- (small, little) + the connecting element -o- + virus was coined in 1965 to describe the decreasingly small objects becoming visible as optical technology improved.  The rotavirus (a wheel-shaped virus causing inflammation of the lining of the intestines), the construct being rota (wheel) + virus dates from 1974.

Diagram of a retrovirus.

The adjective virulent dates from circa 1400 in reference to wounds, ulcers etc (full of corrupt or poisonous matter), from the Latin virulentus (poisonous), from virus; the figurative sense of "violent, spiteful" attested from circa 1600; virulently the related form.  The mysterious reovirus was a noun coined in 1959 by Polish-American medical researcher Dr Albert Sabin (1906-1993), the “reo-“ and acronym for “respiratory enteric orphan”, to describe viruses considered orphans in the sense of not being connected to any of the diseases with which they were associated.  More technical still was the (1977) retrovirus, an evolution of the (1974) retravirus (from re(verse) tra(nscriptase) + connective -o- + virus), explained by it containing reverse transcriptase, an enzyme which uses RNA instead of DNA to encode genetic information, thus reversing the usual pattern.  While these things are usually the work of committees, there seems to be nothing in the public record to suggest why “retro-“ was preferred to “retra-“, the assumption being “retro-“ more explicitly indicated "backwards."

In 2014, while in the South Pacific, Lindsay Lohan contracted Chikungunya, an infection caused by the Chikungunya virus (CHIKV), spread by two types of mosquito.  On Twitter and Instagram, she recommended the use of bug spray.  The condition was first isolated in Tanzania in 1952, the word Chikungunya from the Kimakonde language which translates literally as "to become contorted" although the World Health Organization (WHO) lists the common symptoms as a persistent headache, swollen joints, muscle pain and a rash which typically appears first on the extremities.

Chikungunya virus (CHIKV) assembly and egress.

Not alive in the technical sense defined in biology, a virus is a biological agent which reproduces inside the cells of living hosts.  When infected by a virus, a host cell is forced quickly to produce thousands of identical copies of the original; unlike actual living things, viruses do not have cells that divide, new viruses being assembled in the infected host cell.  Unlike simpler infectious agents, viruses contain genes so they mutate and evolve and thousands are known to exist.  Viruses are tiny, much smaller than bacteria and it can require more than a million of them, side by side, to reach one inch (25 mm) and although a theory of viruses was constructed after French and Russian experiments in the 1880s, it wasn’t until the electron microscope became available in 1931 that the first images were captured.  Where there is life, there are viruses and it’s thought likely they have existed either since, or very shortly after, the first living cells evolved; it’s not impossible the first cellular forms would now, technically, be classified as viruses.  Viruses can be benign and bacteriophages are viruses that infect bacteria, used in eastern Europe since the nineteenth century to treat infection but almost ignored since the development of antibiotics.  With the growth in antibiotic resistance, there’s now renewed interest.  Viruses also perform a useful role in ecology, killing around a fifth of oceanic biomass, the increased respiration in the seas ultimately reducing the atmospheric carbon dioxide by some three gigatons per year.

During the initial 2019 outbreak in Wuhan of what is now called COVID-19, both virus and disease were mostly referred to as "coronavirus", "Wuhan coronavirus" or "Wuhan pneumonia".  There had been a long tradition of naming diseases after the geographical location where they were first reported (Hong Kong flu, Spanish flu etc) but this could be misleading.  The Spanish flu, associated with the pandemic of 1918-1920, was actually first detected elsewhere, either on the World War I battlefields of France or (more probably) a military camp in the United States but, because Spain was a neutral in the conflict, there was no military censorship to limit reporting so warnings about this especially virulent influenza were printed in the Spanish press.  From here, it was eventually picked up and publicized as “Spanish flu” although, doctors there, in an early example of contract tracing, were aware of vectors of transmission and insisted it was the “French flu” because this was where their back-tracing led.  This had no effect beyond Spain and it’s ever since been known as “Spanish flu” although the practice of using geographical references has now been abandoned, a linguistic sanitization which has extended to anything likely to cause offence, the recently topical Monkeypox now called Mpox which seems hardly imaginative.     

Representation of a coronavirus.

In January 2020, the World Health Organization’s (WHO) International Committee on Taxonomy of Viruses (ICTV) recommended the name 2019-nCoV & 2019-nCoV acute respiratory disease as interim names for virus and disease respectively (although “human coronavirus 2019”, “HCoV-19” & “hCoV-19” also exist in the record).  The committee’s recommendation conformed to the conventions adopted after it was decided in 2015, to avoid social stigma, to cease the use of geographical locations or identities associated with specific people(s) in disease-related names.  Although well understood by scientists, the WHO must have thought them a bit much for general use and in February 2020, issued SARS-CoV-2 & COVID-19 as the official nomenclature: CO=corona, VI=virus, D=disease & 19=2019 although for a while, confusingly, documents issued by the WHO sometimes referenced “COVID-19 virus” rather than the correct SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2; the name adopted because of the close genetic relationship to the first SARS outbreak in 2003 (now retrospectively listed as SARS-Cov-1).

Hatter

Hatter (pronounced hat-er)

(1) A maker or seller of hats.

(2) In Australian slang (1) a person who has become eccentric from living alone in a remote area or (2) a person who lives alone in the bush, as a herder or prospector (now archaic and dating from the 1850s, a synecdoche of “mad as a hatter”).

(3) A student or member of the athletic program at Stetson University in Florida.

(4) In dialectical South Scots, to bother; to get someone worked up (and thus related to the modern “to hassle”).

1350–1400: From the Middle English hatter, the construct being hat + -er.  Hat was from the Middle English hat (head covering), from the Old English hæt (head-covering, hat), from the Proto-Germanic hattuz (hat), from the primitive Indo-European kadh (to guard, cover, care for, protect).  It was cognate with the North Frisian hat (hat), the Danish hat (hat), the Swedish hatt (hat), the Icelandic hattur (hat), the Latin cassis (helmet), the Lithuanian kudas (bird's crest or tuft), the Avestan xaoda (hat), the Persian خود‎ (xud) (helmet) and the Welsh cadw (to provide for, ensure).  The –er suffix was from the Middle English –er & -ere, from the Old English -ere, from the Proto-Germanic -ārijaz, thought usually to have been borrowed from Latin –ārius and reinforced by the synonymous but unrelated Old French –or & -eor (the Anglo-Norman variant was -our), from the Latin -(ā)tor, from the primitive Indo-European -tōr.  The –er suffix was added to verbs to create a person or thing that does an action indicated by the root verb; used to form an agent noun.  If added to a noun it usually denoted an occupation.  Hatter is a noun and the rare hattering & hattered are verbs; the noun plural is hatters.

Lindsay Lohan wearing hats.

The synonyms are hatmaker (or hat-maker) & milliner.  As makers of hats, the difference between a hatter and a milliner is that a milliner is a hat-maker specializing (historically bespoke headpieces) in women's headwear (and works at a millinery shop), while a hatter makes hats for men (and works at a hattery).  In the business of selling hats the distinction blurred, especially in the case of operations which dealt with hats for both men and women.  As a retailer, a hatter could deal either exclusively in hats for men for those for both sexes whereas what was sold by a millinery was (at least intended) only for women.  Milliner was from the Middle English Milener (native of Milan), the construct an irregular form of Milan + -er, the link explained by the northern Italian city being the source of many of the fine garments for women imported into England in the late Medieval age.

Depiction of the mad hatter’s tea party.  Created by Lewis Carroll (1832-1898), The Hatter appears in both Alice's Adventures in Wonderland (1865) and Through the Looking-Glass (1871) and though nowhere in the text does the author make reference to a "mad hatter", that is the popular form and not an unreasonable one, given the madness of both The Hatter and the March Hare is confirmed by the Cheshire Cat.  Lewis Carroll was said to be familiar with the traits of madness and the condition suffered by hatters was well known but some literary historians have speculated The Hatter may have been based on an eccentric shop-keeper.  There’s no documentary evidence to support the claim.

Role model JR Ewing (Larry Hagman, 1931–2012) in Stetson hat.

The use of Hatter (usually in the collective Hatters) to describe students or members of the athletic program at Florida’s Stetson University comes from John B Stetson (1830-1906), otherwise famous as the hatter known for his eponymous hats.  The school was in 1883 founded as the DeLand Academy but was in 1889 renamed Stetson after the Mr Hatter joined the Board of Trustees, the change acknowledging his financial largess.  Thus were born the Hatters and the name (informally) extends to the school’s mascot (who is correctly named John B) which wears a Stetson hat, green bandana, and alligator skin boots.  The mascot is considered equal in status to all other members of the school family.

Lindsay Lohan wearing more hats.

The phrase “mad as a hatter” was first recorded in 1829 and is usually attributed to the correlation noted between those engaged in the profession of hat-making and instances of Korsakoff's syndrome induced by the frequency of them handling mercury-contaminated felt.  The nineteenth century speculation of a link with the Old English ātor (poison) or its descendant the Middle English atter (poison, venom,) lacks evidence has long been discredited.  Korsakoff's syndrome was named after the Russian neuropsychiatrist Sergei Sergeievich Korsakoff (1854-1900 (his work on alcoholic psychosis still influential)) who identified the syndrome which is induced by both exposure to mercury and chronic alcohol use.  A neurological disorder of the central nervous system caused by a deficiency of thiamine, the symptoms include amnesia, deficits in explicit memory, tremors and general confabulation.  The fourteenth century variant “mad as a March hare” alludes to the crazy behavior of hares during rutting season, mistakenly thought to be only in March.

In 1888, a hydrochloride-based process which obviated the need to use mercury when processing felt was patented and in France and the UK, just before the turn of the century, laws were passed banning the use of substance in the making of hats but, as an illustration of the way things have changed, in the US, the risk was ignored by hatters and their employers alike, even trade unions making no attempt to end its use.  Only with the onset of World War II when all available mercury was needed for military production did US hat makers voluntarily agree to adopt the long available alternative process which used hydrogen peroxide.